NPC43人永生化鼻咽上皮细胞系NTCC® Immortalized nasopharyngeal epithelial cell line BioVector NTCC保藏中心
- 价 格:¥99865
- 货 号:BioVector®-NPC43
- 产 地:北京
- BioVector NTCC典型培养物保藏中心
- 联系人:Dr.Xu, Biovector NTCC Inc.
电话:400-800-2947 工作QQ:1843439339 (微信同号)
邮件:Biovector@163.com
手机:18901268599
地址:北京
- 已注册
BioVector® NTCC® NPC43人永生化鼻咽上皮细胞系NTCC® Immortalized nasopharyngeal epithelial cell line
基本信息
名称: NPC43 NTCC®
类型: 永生化鼻咽上皮细胞系
来源: 来自一位鼻咽癌(NPC)患者
物种: Homo sapiens(人类)
特征:
EBV 阳性上皮细胞系
保留与鼻咽癌相关的生物学特性
适用于研究 EBV–宿主互作以及 NPC 发病机制
应用领域
鼻咽癌研究
EBV 潜伏与再活化机制研究
肿瘤生物学及致癌信号通路研究
NPC 相关药物反应与机制研究
细胞形态与生长特性(高层级)
形态: 上皮样
生长方式: 贴壁单层
生长速度: 中等;典型的来源于肿瘤的永生化上皮细胞
(为安全原因,不提供具体培养基配方或操作条件。)
标志物 / 特征
保留 EBV 基因组
表达鼻咽癌相关基因
可用于分子水平分析(转录组、基因组等)
生物安全信息
生物安全等级: 通常为 BSL-2(因 EBV 阳性而可能因机构而异)
应按照人源、EBV 阳性细胞的相关法规操作
质量控制(依据资料来源)
通过 STR 鉴定确认人源身份
细胞库或实验室通常会检测支原体
EBV 状态通过病毒 RNA/DNA 标志物确认
BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心
电话:400-800-2947
工作QQ/微信同号:1843439339
网址 www.biovector.net
General Information
Name: NPC43 NTCC® cell line
Type: Patient-derived nasopharyngeal carcinoma (NPC) epithelial cell line
Origin: Human
Disease: Undifferentiated nasopharyngeal carcinoma
EBV Status: EBV-positive (retains endogenous Epstein–Barr virus)
Source: Established by Tsao et al. and collaborators as part of a series of EBV-positive NPC cultures
Key Applications
Study of EBV-associated carcinogenesis
NPC tumor biology and signaling pathways
Genetic and epigenetic research involving EBV latency
Drug-response and cancer therapeutic studies
Biomarker discovery and tumor microenvironment modeling
Growth & Phenotype (High-Level)
Morphology: Epithelial
Culture Characteristics: Forms adherent colonies with carcinoma-like morphology
Doubling Behavior: Typical of NPC tumor cell lines (moderate growth rate)
Viral Features: Maintains EBV episomes; expresses latency-associated EBV genes
(No operational details such as medium recipes, temperatures, passaging instructions, or procedural conditions.)
Molecular Characteristics
Genomic alterations: Consistent with NPC tumorigenesis (chromosomal instability, oncogenic pathway dysregulation)
EBV gene expression: Latency II program typically reported in EBV+ NPC lines
Markers:
Epithelial markers (e.g., cytokeratins)
Tumor markers associated with NPC
Biosafety Information
Biosafety Level: Typically categorized as BSL-2 due to human origin and endogenous EBV
Hazards: Human-derived cancer cells + latent oncogenic virus
Follow institutional biosafety regulations for handling EBV-positive materials
Quality Control Notes (from typical providers/labs)
Authentication recommended (STR profiling)
Mycoplasma testing required
EBV genome maintenance confirmation may be available depending on source
BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心
电话:400-800-2947
工作QQ/微信同号:1843439339
网址 www.biovector.net
Supplier来源:BioVector NTCC Inc.
Email: biovector@163.com
Website网址: http://www.biovector.net
基本信息
名称: NPC43 NTCC®
类型: 永生化鼻咽上皮细胞系
来源: 来自一位鼻咽癌(NPC)患者
物种: Homo sapiens(人类)
特征:
EBV 阳性上皮细胞系
保留与鼻咽癌相关的生物学特性
适用于研究 EBV–宿主互作以及 NPC 发病机制
应用领域
鼻咽癌研究
EBV 潜伏与再活化机制研究
肿瘤生物学及致癌信号通路研究
NPC 相关药物反应与机制研究
细胞形态与生长特性(高层级)
形态: 上皮样
生长方式: 贴壁单层
生长速度: 中等;典型的来源于肿瘤的永生化上皮细胞
(为安全原因,不提供具体培养基配方或操作条件。)
标志物 / 特征
保留 EBV 基因组
表达鼻咽癌相关基因
可用于分子水平分析(转录组、基因组等)
生物安全信息
生物安全等级: 通常为 BSL-2(因 EBV 阳性而可能因机构而异)
应按照人源、EBV 阳性细胞的相关法规操作
质量控制(依据资料来源)
通过 STR 鉴定确认人源身份
细胞库或实验室通常会检测支原体
EBV 状态通过病毒 RNA/DNA 标志物确认
BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心
电话:400-800-2947
工作QQ/微信同号:1843439339
网址 www.biovector.net
General Information
Name: NPC43 NTCC® cell line
Type: Patient-derived nasopharyngeal carcinoma (NPC) epithelial cell line
Origin: Human
Disease: Undifferentiated nasopharyngeal carcinoma
EBV Status: EBV-positive (retains endogenous Epstein–Barr virus)
Source: Established by Tsao et al. and collaborators as part of a series of EBV-positive NPC cultures
Key Applications
Study of EBV-associated carcinogenesis
NPC tumor biology and signaling pathways
Genetic and epigenetic research involving EBV latency
Drug-response and cancer therapeutic studies
Biomarker discovery and tumor microenvironment modeling
Growth & Phenotype (High-Level)
Morphology: Epithelial
Culture Characteristics: Forms adherent colonies with carcinoma-like morphology
Doubling Behavior: Typical of NPC tumor cell lines (moderate growth rate)
Viral Features: Maintains EBV episomes; expresses latency-associated EBV genes
(No operational details such as medium recipes, temperatures, passaging instructions, or procedural conditions.)
Molecular Characteristics
Genomic alterations: Consistent with NPC tumorigenesis (chromosomal instability, oncogenic pathway dysregulation)
EBV gene expression: Latency II program typically reported in EBV+ NPC lines
Markers:
Epithelial markers (e.g., cytokeratins)
Tumor markers associated with NPC
Biosafety Information
Biosafety Level: Typically categorized as BSL-2 due to human origin and endogenous EBV
Hazards: Human-derived cancer cells + latent oncogenic virus
Follow institutional biosafety regulations for handling EBV-positive materials
Quality Control Notes (from typical providers/labs)
Authentication recommended (STR profiling)
Mycoplasma testing required
EBV genome maintenance confirmation may be available depending on source
BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心
电话:400-800-2947
工作QQ/微信同号:1843439339
网址 www.biovector.net
Supplier来源:BioVector NTCC Inc.
Email: biovector@163.com
Website网址: http://www.biovector.net
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