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NPC43人永生化鼻咽上皮细胞系NTCC® Immortalized nasopharyngeal epithelial cell line BioVector NTCC保藏中心

  • 价  格:¥99865
  • 货  号:BioVector®-NPC43
  • 产  地:北京
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BioVector NTCC典型培养物保藏中心
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BioVector® NTCC® NPC43人永生化鼻咽上皮细胞系NTCC® Immortalized nasopharyngeal epithelial cell line

基本信息

名称: NPC43 NTCC®

类型: 永生化鼻咽上皮细胞系

来源: 来自一位鼻咽癌(NPC)患者

物种: Homo sapiens(人类)

特征:

EBV 阳性上皮细胞系

保留与鼻咽癌相关的生物学特性

适用于研究 EBV–宿主互作以及 NPC 发病机制

应用领域

鼻咽癌研究

EBV 潜伏与再活化机制研究

肿瘤生物学及致癌信号通路研究

NPC 相关药物反应与机制研究

细胞形态与生长特性(高层级)

形态: 上皮样

生长方式: 贴壁单层

生长速度: 中等;典型的来源于肿瘤的永生化上皮细胞

(为安全原因,不提供具体培养基配方或操作条件。)

标志物 / 特征

保留 EBV 基因组

表达鼻咽癌相关基因

可用于分子水平分析(转录组、基因组等)

生物安全信息

生物安全等级: 通常为 BSL-2(因 EBV 阳性而可能因机构而异)

应按照人源、EBV 阳性细胞的相关法规操作

质量控制(依据资料来源)

通过 STR 鉴定确认人源身份

细胞库或实验室通常会检测支原体

EBV 状态通过病毒 RNA/DNA 标志物确认

BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心
电话:400-800-2947
工作QQ/微信同号:1843439339
网址 www.biovector.net

General Information

Name: NPC43 NTCC® cell line

Type: Patient-derived nasopharyngeal carcinoma (NPC) epithelial cell line

Origin: Human

Disease: Undifferentiated nasopharyngeal carcinoma

EBV Status: EBV-positive (retains endogenous Epstein–Barr virus)

Source: Established by Tsao et al. and collaborators as part of a series of EBV-positive NPC cultures

Key Applications

Study of EBV-associated carcinogenesis

NPC tumor biology and signaling pathways

Genetic and epigenetic research involving EBV latency

Drug-response and cancer therapeutic studies

Biomarker discovery and tumor microenvironment modeling

Growth & Phenotype (High-Level)

Morphology: Epithelial

Culture Characteristics: Forms adherent colonies with carcinoma-like morphology

Doubling Behavior: Typical of NPC tumor cell lines (moderate growth rate)

Viral Features: Maintains EBV episomes; expresses latency-associated EBV genes

(No operational details such as medium recipes, temperatures, passaging instructions, or procedural conditions.)

Molecular Characteristics

Genomic alterations: Consistent with NPC tumorigenesis (chromosomal instability, oncogenic pathway dysregulation)

EBV gene expression: Latency II program typically reported in EBV+ NPC lines

Markers:

Epithelial markers (e.g., cytokeratins)

Tumor markers associated with NPC

Biosafety Information

Biosafety Level: Typically categorized as BSL-2 due to human origin and endogenous EBV

Hazards: Human-derived cancer cells + latent oncogenic virus

Follow institutional biosafety regulations for handling EBV-positive materials

Quality Control Notes (from typical providers/labs)

Authentication recommended (STR profiling)

Mycoplasma testing required

EBV genome maintenance confirmation may be available depending on source

BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心
电话:400-800-2947
工作QQ/微信同号:1843439339
网址 www.biovector.net


Supplier来源:BioVector NTCC Inc.
Email: biovector@163.com
Website网址: http://www.biovector.net

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