MOLP-2-Luc人多发性骨髓瘤荧光素酶稳定表达细胞株NTCC® human multiple myeloma cell line BioVector NTCC保藏中心
- 价 格:¥799865
- 货 号:BioVector®-MOLP-2-Luc
- 产 地:北京
- BioVector NTCC典型培养物保藏中心
- 联系人:Dr.Xu, Biovector NTCC Inc.
电话:400-800-2947 工作QQ:1843439339 (微信同号)
邮件:Biovector@163.com
手机:18901268599
地址:北京
- 已注册
BioVector® NTCC® MOLP-2-Luc人多发性骨髓瘤荧光素酶稳定表达细胞株NTCC® human multiple myeloma cell line
基本信息
名称: MOLP-2-Luc NTCC® cell line
来源细胞系: MOLP-2(人多发性骨髓瘤细胞系)
物种: Homo sapiens(人)
类型: B 细胞样、悬浮生长的肿瘤细胞
改造: 稳定表达萤光素酶(Luciferase),用于体内/体外生物发光成像
主要应用
多发性骨髓瘤机制研究
药物筛选与敏感性评价
动物实验中的肿瘤负荷实时成像(BLI)
细胞信号通路与肿瘤微环境研究
生长特性(高层级描述)
生长方式: 悬浮
倍增时间: 中等速度
表型特征: 高度表达骨髓瘤相关标记;携带可测量的生物发光信号
发光特性: 适合进行荧光素底物诱导的原位发光检测
生物安全信息
生物安全等级: 一般为 BSL-2(因有人源与转基因成分,具体依赖机构规定)
风险提示: 作为肿瘤细胞株,需遵守标准细胞培养安全规范
质量控制(依供应商而定)
真菌/细菌/支原体检测
发光信号稳定性检测
细胞身份验证(STR 分析)
冻存与复苏活力检测
BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心
电话:400-800-2947
工作QQ/微信同号:1843439339
网址 www.biovector.net
General Information
Name: MOLP-2-Luc NTCC® human multiple myeloma cell line
Parent Line: MOLP-2 (human multiple myeloma cell line)
Modification: Stably transduced to express firefly luciferase (Luc)
Species: Human (Homo sapiens)
Disease Origin: Plasma-cell leukemia / multiple myeloma
Cell Type: Suspension; malignant plasma cells
Applications
In vivo bioluminescence imaging (BLI) models of multiple myeloma
Drug efficacy screening using luminescence readouts
Tumor growth tracking in animal studies
Mechanistic studies of myeloma progression and plasma-cell biology
Key Features
Stable luciferase expression enables non-invasive quantification of viable cell numbers
Derived from a human hematologic malignancy, retaining myeloma-related markers
Suitable for xenograft models commonly used in cancer-research pipelines
Biological Characteristics (High-Level)
Morphology: Non-adherent, spherical plasma-like cells
Growth Mode: Suspension
Doubling Time: Consistent with malignant B-cell lines (varies by provider)
Markers (parent line):
CD38⁺, CD138⁺ typical of plasma cells
Immunoglobulin-producing phenotype
Genomic/Protein Modification:
Firefly luciferase integrated for luminescence assays
Biosafety & Handling
Biosafety Level: Typically BSL-2 (human cancer cell line)
Local institutional biosafety guidelines may differ
Hazards: Human-derived, malignant; treat as potentially infectious material
Standard PPE and biological-safety procedures recommended at all times
Authentication
Parent line originated from a multiple myeloma patient
Vendors usually provide:
STR profiling
Luciferase activity confirmation
Mycoplasma testing
Quality Control Notes (vendor-dependent)
Authentication of luciferase expression
Viability ≥ provider-specified threshold
Sterility panel: bacteria, fungi, mycoplasma
BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心
电话:400-800-2947
工作QQ/微信同号:1843439339
网址 www.biovector.net
Supplier来源:BioVector NTCC Inc.
Email: biovector@163.com
Website网址: http://www.biovector.net
基本信息
名称: MOLP-2-Luc NTCC® cell line
来源细胞系: MOLP-2(人多发性骨髓瘤细胞系)
物种: Homo sapiens(人)
类型: B 细胞样、悬浮生长的肿瘤细胞
改造: 稳定表达萤光素酶(Luciferase),用于体内/体外生物发光成像
主要应用
多发性骨髓瘤机制研究
药物筛选与敏感性评价
动物实验中的肿瘤负荷实时成像(BLI)
细胞信号通路与肿瘤微环境研究
生长特性(高层级描述)
生长方式: 悬浮
倍增时间: 中等速度
表型特征: 高度表达骨髓瘤相关标记;携带可测量的生物发光信号
发光特性: 适合进行荧光素底物诱导的原位发光检测
生物安全信息
生物安全等级: 一般为 BSL-2(因有人源与转基因成分,具体依赖机构规定)
风险提示: 作为肿瘤细胞株,需遵守标准细胞培养安全规范
质量控制(依供应商而定)
真菌/细菌/支原体检测
发光信号稳定性检测
细胞身份验证(STR 分析)
冻存与复苏活力检测
BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心
电话:400-800-2947
工作QQ/微信同号:1843439339
网址 www.biovector.net
General Information
Name: MOLP-2-Luc NTCC® human multiple myeloma cell line
Parent Line: MOLP-2 (human multiple myeloma cell line)
Modification: Stably transduced to express firefly luciferase (Luc)
Species: Human (Homo sapiens)
Disease Origin: Plasma-cell leukemia / multiple myeloma
Cell Type: Suspension; malignant plasma cells
Applications
In vivo bioluminescence imaging (BLI) models of multiple myeloma
Drug efficacy screening using luminescence readouts
Tumor growth tracking in animal studies
Mechanistic studies of myeloma progression and plasma-cell biology
Key Features
Stable luciferase expression enables non-invasive quantification of viable cell numbers
Derived from a human hematologic malignancy, retaining myeloma-related markers
Suitable for xenograft models commonly used in cancer-research pipelines
Biological Characteristics (High-Level)
Morphology: Non-adherent, spherical plasma-like cells
Growth Mode: Suspension
Doubling Time: Consistent with malignant B-cell lines (varies by provider)
Markers (parent line):
CD38⁺, CD138⁺ typical of plasma cells
Immunoglobulin-producing phenotype
Genomic/Protein Modification:
Firefly luciferase integrated for luminescence assays
Biosafety & Handling
Biosafety Level: Typically BSL-2 (human cancer cell line)
Local institutional biosafety guidelines may differ
Hazards: Human-derived, malignant; treat as potentially infectious material
Standard PPE and biological-safety procedures recommended at all times
Authentication
Parent line originated from a multiple myeloma patient
Vendors usually provide:
STR profiling
Luciferase activity confirmation
Mycoplasma testing
Quality Control Notes (vendor-dependent)
Authentication of luciferase expression
Viability ≥ provider-specified threshold
Sterility panel: bacteria, fungi, mycoplasma
BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心
电话:400-800-2947
工作QQ/微信同号:1843439339
网址 www.biovector.net
Supplier来源:BioVector NTCC Inc.
Email: biovector@163.com
Website网址: http://www.biovector.net
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