首页 » MOLP-2-Luc人多发性骨髓瘤荧光素酶稳定表达细胞株NTCC® human multiple myeloma cell line BioVector NTCC保藏中心

MOLP-2-Luc人多发性骨髓瘤荧光素酶稳定表达细胞株NTCC® human multiple myeloma cell line BioVector NTCC保藏中心

  • 价  格:¥799865
  • 货  号:BioVector®-MOLP-2-Luc
  • 产  地:北京
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BioVector® NTCC® MOLP-2-Luc人多发性骨髓瘤荧光素酶稳定表达细胞株NTCC® human multiple myeloma cell line

基本信息

名称: MOLP-2-Luc NTCC® cell line

来源细胞系: MOLP-2(人多发性骨髓瘤细胞系)

物种: Homo sapiens(人)

类型: B 细胞样、悬浮生长的肿瘤细胞

改造: 稳定表达萤光素酶(Luciferase),用于体内/体外生物发光成像

主要应用

多发性骨髓瘤机制研究

药物筛选与敏感性评价

动物实验中的肿瘤负荷实时成像(BLI)

细胞信号通路与肿瘤微环境研究

生长特性(高层级描述)

生长方式: 悬浮

倍增时间: 中等速度

表型特征: 高度表达骨髓瘤相关标记;携带可测量的生物发光信号

发光特性: 适合进行荧光素底物诱导的原位发光检测

生物安全信息

生物安全等级: 一般为 BSL-2(因有人源与转基因成分,具体依赖机构规定)

风险提示: 作为肿瘤细胞株,需遵守标准细胞培养安全规范

质量控制(依供应商而定)

真菌/细菌/支原体检测

发光信号稳定性检测

细胞身份验证(STR 分析)

冻存与复苏活力检测

BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心
电话:400-800-2947
工作QQ/微信同号:1843439339
网址 www.biovector.net

General Information

Name: MOLP-2-Luc NTCC® human multiple myeloma cell line

Parent Line: MOLP-2 (human multiple myeloma cell line)

Modification: Stably transduced to express firefly luciferase (Luc)

Species: Human (Homo sapiens)

Disease Origin: Plasma-cell leukemia / multiple myeloma

Cell Type: Suspension; malignant plasma cells

Applications

In vivo bioluminescence imaging (BLI) models of multiple myeloma

Drug efficacy screening using luminescence readouts

Tumor growth tracking in animal studies

Mechanistic studies of myeloma progression and plasma-cell biology

Key Features

Stable luciferase expression enables non-invasive quantification of viable cell numbers

Derived from a human hematologic malignancy, retaining myeloma-related markers

Suitable for xenograft models commonly used in cancer-research pipelines

Biological Characteristics (High-Level)

Morphology: Non-adherent, spherical plasma-like cells

Growth Mode: Suspension

Doubling Time: Consistent with malignant B-cell lines (varies by provider)

Markers (parent line):

CD38⁺, CD138⁺ typical of plasma cells

Immunoglobulin-producing phenotype

Genomic/Protein Modification:

Firefly luciferase integrated for luminescence assays

Biosafety & Handling

Biosafety Level: Typically BSL-2 (human cancer cell line)

Local institutional biosafety guidelines may differ

Hazards: Human-derived, malignant; treat as potentially infectious material

Standard PPE and biological-safety procedures recommended at all times

Authentication

Parent line originated from a multiple myeloma patient

Vendors usually provide:

STR profiling

Luciferase activity confirmation

Mycoplasma testing

Quality Control Notes (vendor-dependent)

Authentication of luciferase expression

Viability ≥ provider-specified threshold

Sterility panel: bacteria, fungi, mycoplasma

BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心
电话:400-800-2947
工作QQ/微信同号:1843439339
网址 www.biovector.net

Supplier来源:BioVector NTCC Inc.
Email: biovector@163.com
Website网址: http://www.biovector.net

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