pcDNA3-HMGB1 BioVector®基因表达质粒-BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心

pcDNA3-HMGB1 BioVector®基因表达质粒-BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心

pcDNA3-HMGB1 is a plasmid vector that encodes the human HMGB1 gene. HMGB1 (High Mobility Group Box 1) is a protein that plays a role in various cellular processes, including gene transcription, DNA repair, and inflammation.

Key Features of pcDNA3-HMGB1:

• pcDNA3 Vector: This is a widely used mammalian expression vector. It contains a strong promoter (CMV promoter) that drives high levels of gene expression in mammalian cells.

• HMGB1 Gene: This gene encodes the HMGB1 protein, a nuclear protein involved in various cellular functions.

• Applications: pcDNA3-HMGB1 is used in research to study the function of HMGB1, its role in various diseases, and to develop potential therapeutic targets.

Research Applications:

• Overexpression of HMGB1: This plasmid can be used to overexpress HMGB1 in cells to investigate its effects on cellular processes.

• Knockdown of HMGB1: By expressing shRNA against HMGB1, this plasmid can be used to study the effects of HMGB1 knockdown.

• Drug Discovery: pcDNA3-HMGB1 can be used to screen for drugs that target HMGB1 or its downstream signaling pathways.

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