RTC274 NTCC®人横纹肌肉瘤细胞株human rhabdomyosarcoma cell line BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心
- 价 格：¥99850
- 货 号：NTCC®RTC274
- 产 地：北京
- BioVector NTCC典型培养物保藏中心
- 联系人：Dr.Xu, Biovector NTCC Inc.
电话：400-800-2947 工作QQ:1843439339 (微信同号)
邮件：Biovector@163.com
手机：18901268599
地址：北京
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RTC274 NTCC®人横纹肌肉瘤细胞株human rhabdomyosarcoma cell line
BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心
The RTC274 cell line is a human rhabdomyosarcoma cell line. It has been widely used in cancer research, particularly in studies related to rhabdomyosarcoma.
Key Characteristics:
Origin: Derived from a human alveolar rhabdomyosarcoma
Morphology: Epithelial-like cells
Tumorigenicity: Can form tumors in nude mice
Genetic Alterations: Characterized by specific chromosomal translocations, typically involving the PAX3-FOXO1 fusion gene.
Applications in Research:
The RTC274 cell line has been used in various research areas, including:
Rhabdomyosarcoma research: Studying the molecular mechanisms of rhabdomyosarcoma development and progression, particularly those driven by the PAX3-FOXO1 fusion.
Drug development and screening: Evaluating the efficacy and toxicity of potential anticancer drugs.
Cell biology: Investigating cellular processes such as cell cycle regulation, apoptosis, and signal transduction pathways.
Limitations:
Immortalized cell line: May not perfectly reflect the behavior of primary tumor cells.
Potential for genetic drift: Prolonged culture can lead to changes in the cell line's genetic makeup.
生产厂家Supplier:
BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心
E-mail:BioVector@163.com
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