GEN2.2 NTCC®人浆细胞样树突状细胞株human plasmacytoid dendritic cell (pDC) line BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心

GEN2.2 NTCC®人浆细胞样树突状细胞株human plasmacytoid dendritic cell (pDC) line

BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心

The GEN2.2 cell line is a human plasmacytoid dendritic cell (pDC) line.

• Plasmacytoid Dendritic Cells (pDCs): These are a specialized type of white blood cell that plays a crucial role in the innate immune system. They are known for their ability to produce large amounts of type I interferons (IFN-α/β) in response to viral infections.

• Significance of GEN2.2 Cell Line:

  • Research Model: The GEN2.2 cell line serves as an in vitro model for studying pDC biology and function.

  • Viral Infection Studies: It is used to investigate the interactions between pDCs and viruses, including how pDCs respond to viral infections and contribute to antiviral immunity.

  • Immunotherapy Research: It can be employed to study the role of pDCs in immune responses and to develop new immunotherapeutic approaches for treating viral infections and other diseases.

• Key Characteristics:

  • Phenotype: Expresses many of the surface markers characteristic of primary pDCs.

  • Functional Properties: Retains some of the functional properties of primary pDCs, such as the ability to produce type I interferons in response to viral stimulation.

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