RNase H1 mammalian expression plasmid BioVector®基因真核表达质粒 BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心

RNase H1 mammalian expression plasmid BioVector®基因真核表达质粒

BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心

An RNase H1 mammalian expression plasmid is a genetic construct designed to express the RNase H1 enzyme in mammalian cells.

Key Components:

• RNase H1 Gene: The plasmid contains the cDNA sequence encoding the human RNase H1 enzyme.

• Mammalian Promoter: A strong mammalian promoter, such as the cytomegalovirus (CMV) promoter, drives the expression of the RNase H1 gene in mammalian cells.

• Other Elements: The plasmid may also contain other elements such as:

  • Antibiotic Resistance Gene: Allows for selection of cells that have taken up the plasmid.

  • Origin of Replication: Enables the plasmid to replicate in bacteria.

  
  

Applications:

• Studying RNase H1 Function: These plasmids can be used to investigate the role of RNase H1 in various cellular processes, such as DNA replication, transcription, and RNA processing.

• Overexpression Studies: Overexpressing RNase H1 in mammalian cells can help to elucidate its function and identify potential cellular pathways that are regulated by this enzyme.

• Gene Therapy: In theory, these plasmids could be used for gene therapy to correct deficiencies in RNase H1 activity, although this is still an area of active research.

Significance:

RNase H1 plays crucial roles in various cellular processes, including DNA replication and RNA metabolism. Studying RNase H1 function and its regulation is important for understanding fundamental cellular processes and may have implications for human health and disease.

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BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心

E-mail:BioVector@163.com

http://www.biovector.net