KUP5 NTCC®永生化小鼠库普弗细胞株 BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心

NTCC® KUP5永生化小鼠库普弗细胞株

BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心

NTCC® KUP5 is an immortalized mouse Kupffer cell line.

• Kupffer cells: These are specialized macrophages found in the liver. They play a crucial role in liver function, including:

  • Phagocytosis (engulfing and destroying foreign particles)

  • Immune response

  • Metabolism

  • Iron storage

• Immortalized: This means the cells can divide indefinitely in culture, making them a valuable tool for research.

• Origin: KUP5 cells were derived from the liver of a C57BL/6 mouse.

• Characteristics:

  • Exhibit typical macrophage morphology

  • Express macrophage markers (Mac-1, F4/80)

  • Phagocytic activity

  • Release inflammatory cytokines in response to stimulation

• Research Applications: KUP5 cells are used in various research areas, including:

  • Liver diseases

  • Immunology

  • Drug metabolism

  • Toxicology

  • Inflammation

By providing a stable and readily available source of Kupffer cells, the KUP5 cell line allows researchers to study the functions of these cells in vitro and gain insights into liver biology and disease.

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BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心

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