SF8628 Human DIPG H3.3-K27M NTCC® Cell Line人弥漫型内因性桥脑神经胶细胞瘤细胞株-BioVector NTCC Inc.

SF8628 Human DIPG H3.3-K27M NTCC® Cell Line人弥漫型内因性桥脑神经胶细胞瘤细胞株-BioVector NTCC Inc.

SF8628 is a human glioma cell line derived from a pediatric patient with diffuse intrinsic pontine glioma (DIPG).This specific cell line is particularly significant due to its harboring of the H3.3K27M mutation, a common genetic alteration found in DIPG.

Key Features:

• H3.3K27M Mutation: This mutation leads to altered histone modification patterns, contributing to the aggressive nature of DIPG.

• Pediatric Origin: Derived from a pediatric patient, making it a valuable tool for studying pediatric brain tumors.

  
  

• Research Applications:

  • Drug Discovery:Used to screen for potential therapeutic agents targeting DIPG.

    
    

  • Mechanism of Disease: Investigating the molecular mechanisms underlying DIPG, particularly those related to the H3.3K27M mutation.

  • Model Systems: Developing in vitro models to study the effects of different treatments on DIPG cells.

  
  

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生产厂家Supplier:

BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心

E-mail:BioVector@163.com

http://www.biovector.net