pegCTNNB1 S45del BioVector®哺乳动物表达质粒-BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心
- 价 格:¥49850
- 货 号:BioVector®pegCTNNB1 S45del
- 产 地:北京
- BioVector NTCC典型培养物保藏中心
- 联系人:Dr.Xu, Biovector NTCC Inc.
电话:400-800-2947 工作QQ:1843439339 (微信同号)
邮件:Biovector@163.com
手机:18901268599
地址:北京
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BioVector®pegCTNNB1 S45del is a genetic variant that affects the CTNNB1 gene, which provides instructions for making a protein called beta-catenin. This protein plays a role in cell adhesion and signaling pathways that control cell growth and development.
The S45del variant causes a deletion of the amino acid serine at position 45 in the beta-catenin protein. This deletion disrupts the normal function of the protein, leading to increased levels of beta-catenin in cells. Increased levels of beta-catenin can lead to uncontrolled cell growth and the development of cancer.
The S45del variant has been found to be associated with several types of cancer, including colorectal cancer, hepatocellular carcinoma, and pancreatic cancer. It is also associated with a rare inherited disorder called familial adenomatous polyposis (FAP), which causes the formation of numerous polyps in the colon and rectum.
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BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心
E-mail:BioVector@163.com
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