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pGreenFire1-COL2A1 promoter BioVector®人II型胶原启动子COL2A1 promoter的表达质粒-BioVector NTCC Inc.

  • 价  格:¥79850
  • 货  号:BioVector® pGreenFire1-COL2A1 promoter
  • 产  地:北京
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pGreenFire1-COL2A1 promoter BioVector®人II型胶原启动子COL2A1 promoter的表达质粒-BioVector NTCC Inc.


在基于 COL2A1 的软骨形成响应启动子控制下的慢病毒表达质粒。

Vector type Mammalian Expression, Lentiviral, Luciferase

Growth in Bacteria

Bacterial Resistance(s) Ampicillin, 100 μg/mL

Growth Temperature 37°C

Growth Strain  NEB Stable

Copy number High Copy


The COL2A1 gene's promoter contains a TATA box and is a target of inhibition by interferon-gamma in human chondrocytes. The COL2A1 gene encodes the alpha-1 chain of type II collagen, which is a protein that provides strength and structure to connective tissues. Some promoters and enhancers for the COL2A1 gene include:
  • GH12J047977: A promoter/enhancer with a TSS distance of +28.8 kb

  • GH12J047962: A promoter/enhancer with a TSS distance of +41.6 kb

  • GH12J047959: An enhancer with a TSS distance of +46.2 kb

  • GH12J047953: An enhancer with a TSS distance of +51.7 kb


The COL2A1 gene is active in differentiating chondrocytes, notochord, and submandibular glands. Mutations in the COL2A1 gene can be associated with conditions such as achondrogenesis, chondrodysplasia, and osteoarthritis.

A summary of the organization of promoter and enhancer elements of the... |  Download Scientific Diagram

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