OPM-1人源浆细胞性骨髓瘤细胞株NTCC® Human Plasma cell myeloma cell line-BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心

价　　格：¥98950
货　　号：NTCC®-5210 OPM-1
产　　地：北京

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OPM-1人源浆细胞性骨髓瘤细胞株NTCC® Human Plasma cell myeloma cell line-BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心

Cell line name

OPM-1

Synonyms

OPM1

Accession

CVCL_5210

Resource Identification Initiative

To cite this cell line use: OPM-1 (RRID:CVCL_5210)

Comments

Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Characteristics: Produces Ig lambda.
Doubling time: 36-42 hours (PubMed=3926660).
Omics: Array-based CGH.
Omics: Deep exome analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.

Sequence variations

Mutation; HGNC; 1787; CDKN2A; Simple; p.His83Tyr (c.247C>T) (p.Ala97Val, c.290C>T); ClinVar=VCV000376307; Zygosity=Heterozygous (DepMap=ACH-000057).
Mutation; HGNC; 3690; FGFR3; Simple; p.Lys650Glu (c.1948A>G); ClinVar=VCV000016331; Zygosity=Heterozygous (PubMed=11157491; DepMap=ACH-000057).
Mutation; HGNC; 6768; SMAD2; Simple; p.Leu87Arg (c.260T>G); Zygosity=Heterozygous (DepMap=ACH-000057).
Mutation; HGNC; 11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Homozygous (DepMap=ACH-000057).

Genome ancestry

Source: PubMed=30894373