HEC6人子宫内膜样腺癌细胞株NTCC® Endometrial endometrioid adenocarcinoma cell line BioVector NTCC质粒载体菌种细胞基因保藏中心

BioVector® NTCC® HEC6人子宫内膜样腺癌细胞株NTCC® Endometrial endometrioid adenocarcinoma cell line

Cell line nameHEC-6
SynonymsHEC6
AccessionNTCC®_2931
Resource Identification InitiativeTo cite this cell line use: HEC-6 (RRID:NTCC®_2931)
CommentsPart of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: MD Anderson Cell Lines Project.
Population: Japanese.
Doubling time: 52 hours (PubMed=862644).
Microsatellite instability: Instable (MSI) (PubMed=31068700).
Omics: Deep exome analysis.
Omics: Deep quantitative proteome analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Endometrium; UBERON=UBERON_0001295.
Sequence variations
Mutation; HGNC; 2514; CTNNB1; Simple; p.Asp32Val (c.95A>T); ClinVar=VCV000376230; Zygosity=Heterozygous (DepMap=ACH-000984).
Mutation; HGNC; 8975; PIK3CA; Simple; p.Arg108His (c.323G>A); ClinVar=VCV000280875; Zygosity=Heterozygous (DepMap=ACH-000984).
Mutation; HGNC; 8975; PIK3CA; Simple; p.Cys420_Pro421del (c.1258_1263delTGTCCA); Zygosity=Heterozygous (DepMap=ACH-000984).
Mutation; HGNC; 6407; KRAS; Simple; p.Val160Ala (c.479T>C); Zygosity=Heterozygous (DepMap=ACH-000984).
Mutation; HGNC; 9588; PTEN; Simple; p.Glu288fs*3 (c.863delA); Zygosity=Heterozygous (DepMap=ACH-000984).
Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (DepMap=ACH-000984).
HLA typingSource: PubMed=26589293
Class I
HLA-AA*24:02,24:02
HLA-BB*59:01,59:01
HLA-CC*01:02,01:02
Class II
HLA-DQDQA1*05:02,05:02
DQB1*04:01,04:01
HLA-DRDRB1*04:05,11:04
Genome ancestrySource: PubMed=30894373

Origin% genome
African0
Native American0
East Asian, North75.17
East Asian, South23.89
South Asian0
European, North0
European, South0.94
DiseaseEndometrial endometrioid adenocarcinoma, variant with squamous differentiation (NCIt: C6290)
Species of originHomo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cellFemale
Age at sampling48Y
CategoryCancer cell line

Supplier来源:BioVector NTCC Inc.
Email: biovector@163.com
Website网址: http://www.biovector.net