HL-60/Vinc成人急性髓性白血病细胞株Adult acute myeloid leukemia cell line BioVector NTCC质粒载体菌种细胞基因保藏中心

BioVector® NTCC® HL-60/Vinc成人急性髓性白血病细胞株Adult acute myeloid leukemia cell line

Cell line name HL-60/Vinc
Synonyms HL60/Vinc
Accession NTCC®_4967
Resource Identification Initiative To cite this cell line use: HL-60/Vinc (NTCC®_4967)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:28445; Vincristine (VCR).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
Gene deletion; HGNC; 11998; TP53; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
Disease Adult acute myeloid leukemia (NCIt: C9154)
Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0002 (HL-60)
Sex of cell Female
Age at sampling 36Y
Category Cancer cell line

Supplier来源:BioVector NTCC Inc.
Email: biovector@163.com
Website网址: http://www.biovector.net