RKN细胞株NTCC® cell line BioVector NTCC质粒载体菌种细胞基因保藏中心

BioVector® NTCC® RKN细胞株NTCC® cell line

Cell line name RKN
Accession NTCC®_3156
Resource Identification Initiative To cite this cell line use: RKN (RRID:NTCC®_3156)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Population: Japanese.
Doubling time: 65 hours (PubMed=25984343); 31.2 hours (JCRB=JCRB0176).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: CRISPR phenotypic screen.
Omics: Deep exome analysis.
Omics: Deep quantitative proteome analysis.
Omics: DNA methylation analysis.
Omics: shRNA library screening.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (Cosmic-CLP=1298539; DepMap=ACH-000505).
Mutation; HGNC; 11730; TERT; Simple; c.-57A>C (c.161A>C) (A161C); ClinVar=VCV000242210; Zygosity=Unspecified; Note=In promoter (PubMed=31068700).
Mutation; HGNC; 11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Homozygous (Cosmic-CLP=1298539; DepMap=ACH-000505).
HLA typing Source: PubMed=26589293
Class I
HLA-A A*33:03,33:03
HLA-B B*44:03,44:03
HLA-C C*14:03,14:03
Class II
HLA-DQ DQB1*04:01,04:01
HLA-DR DRB1*03:42,03:42
Genome ancestry Source: PubMed=30894373

Origin % genome
African 0
Native American 0
East Asian, North 77.67
East Asian, South 22.19
South Asian 0
European, North 0
European, South 0.14
Disease Ovarian leiomyosarcoma (NCIt: C5234)
Leiomyosarcoma (ORDO: Orphanet_64720)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 45Y
Category Cancer cell line

Supplier来源:BioVector NTCC Inc.
Email: biovector@163.com
Website网址: http://www.biovector.net