MCL1‐BIM信号通路稳定表达细胞株NTCC® Signaling Pathway Stable Cell Line-MCL1‐BIM药物靶点-BioVector NTCC细胞库

Cell Line Name：NTCC® MCL1‐BIM信号通路稳定表达细胞株NTCC® Signaling Pathway Stable Cell Line

Target药物靶点：MCL1‐BIM
Cat#货号:NTCC®-S-MCL1‐BIM
Size/Quantity数量: 1 Flask / 2 Vials
Biosafety Level生物安全级别: 1
Shipping Info运输方式: RT/Dry Ice
Storage储存方式: RT/Liquid Nitrogen
Application用途:Protein Binding, Target Engagement
Cellular pathway signaling constitutes key mechanisms that transfer biological information within cells for intracellular responses crucial in many physiological processes, including cell proliferation, differentiation, metabolic control, and apoptosis. Cell signaling pathways are activated when ligands (e.g., cytokines, growth factors, or hormones) bind to specific receptors on the cell surface. Detecting specific stimuli via intracellular signal pathways becomes paramount in interrogating the mechanism of action of the target ligand/receptor interaction for advancing drug discovery and development in many pathophysiologic and pharmacologic mechanisms. BioVector NTCC Inc. offers a comprehensive collection of cell-based pathway indicator assays designed to detect activation or inhibition of complex signal transduction pathways in response to a small molecule or biologic. The assays are based on the established NTCC®PathHunter technology, and feature indicator cell lines used in p Product Highlights Homogeneous Assays – Simple, no wash HTS-friendly protocols with a sensitive chemiluminescent read-out Multiple Assay Types – Binding and functional (direct and reporter-based) cell-based assay with no need for antibodies, fixing, or imaging Fast, Superior Results – Rapid assay with short compound incubation times, high signal-to-background, and no false positives High Specificity – Whole cell, non-ELISA assays with increased target specificityathway assays that enable you to measure distinct events within a variety of pathways associated with immune response, compound toxicity, cholesterol metabolism, antioxidant function, DNA damage, and more. Combined with a fast and simple chemiluminescent detection, these signaling pathway assays enable the generation of cellular pathway selectivity profiles and obtain a comprehensive understanding of different compounds or biologics for receptor-proximal or -distal events without relying on complex phenotypic screens.
Cell Line: 
EXpress Kit:
Bioassay Kit生物检测试剂盒:
Protein蛋白:
Cell Type细胞类型: NTCC® Signaling Pathway Stable Cell Line
Source组织来源:
Specification规格:
Cell Images细胞图片:
Complete Growth Medium完全培养基: NTCC® MCL1‐BIM Stable Cells Complete Medium
Subculturing传代方法:
Cryopreservation冻存方法:Freeze medium: Complete growth medium supplemented with 5% (v/v) DMSO
Storage temperature: RT/Liquid nitrogen vapor phase
Culture Conditions培养条件:Atmosphere: air, 95%; carbon dioxide (CO2), 5%
Temperature: 37.0°C
STR Profile鉴定数据:
References参考文献:

Supplier供应商:
BioVector质粒载体菌株细胞蛋白抗体基因保藏中心
NTCC典型培养物保藏中心
Tel电话：400-800-2947
Email：Biovector@163.com
http://www.biovector.net