Nav1.1离子通道稳定表达细胞株NTCC® Ion Channel Stable Cell Line-Nav1.1药物靶点-BioVector NTCC细胞库

Cell Line Name：NTCC® Nav1.1 Ion Channel Stable Cell Line离子通道稳定表达细胞株

Target药物靶点：Nav1.1
Cat#货号:NTCC®-I-Nav1.1
Size/Quantity数量: 1 Flask / 2 Vials
Biosafety Level生物安全级别: 1
Shipping Info运输方式: RT/Dry Ice
Storage储存方式: RT/Liquid Nitrogen
Application用途:Electrophysiological studies
High-Quality NTCC® PrecisION Cell Lines for Target Discovery, Hit Screening, Lead Optimization, and Safety Studies. Ion channels continue to be an important therapeutic target for a wide range of indications, including arrhythmia, hypertension, local anesthesia, pain, stroke, epilepsy, depression, bipolar disorder, cystic fibrosis, cardiac arrhythmias, COPD, autoimmune disorders, and diabetes. They are an appealing target to develop therapeutics against rare channelopathies, since many of these diseases are caused by the mutation of a single gene. Ion channels not only constitute a significant class of drug targets, they are also critical for evaluating drug safety, including being part of the U.S. FDA required safety testing for any drug targeted against human disease. NTCC®’s comprehensive portfolio of functionally validated ion channel products is comprised of optimized and NTCC®PrecisION stable ion-channel cell lines for use in cell-based assays, NTCC® PathHunter pharmacotrafficking assays for pharmacochaperone discovery, and an hERG ion channel membrane preps for binding studies. The vast ion channel product solutions include assessment of voltage-gated, ligand-gated, and several other targets for screening ion channel inhibitors for your drug discovery and safety applications. The ion channel cell lines are pharmacologically and functionally validated using in-house discovery and safety services laboratories. Their biophysical and pharmacological properties are characterized electrophysiologically using conventional manual patch-clamp and multiple automated patch-clamp platforms by experienced electrophysiologists in both BioVector NTCC Inc. services and BioVector NTCC Inc. products laboratories.
Cell Line: 
Membrane Prep:
Bioassay Kit生物检测试剂盒:
Other Collection No.其他编号:
Cell Type细胞类型: Ion Channel Stable Cell Line
Source组织来源:
Specification规格:
Cell Images细胞图片:
Complete Growth Medium完全培养基: NTCC® Nav1.1 Stable Cells Complete Medium
Subculturing传代方法:
Cryopreservation冻存方法:Freeze medium: Complete growth medium supplemented with 5% (v/v) DMSO
Storage temperature: RT/Liquid nitrogen vapor phase
Culture Conditions培养条件:Atmosphere: air, 95%; carbon dioxide (CO2), 5%
Temperature: 37.0°C
STR Profile鉴定数据:
References参考文献:

Supplier供应商:
BioVector质粒载体菌株细胞蛋白抗体基因保藏中心
NTCC典型培养物保藏中心
Tel电话：400-800-2947
Email：Biovector@163.com
http://www.biovector.net