AG08526阿尔茨海默病； AD B淋巴细胞LCL Cell Line细胞株-BioVector NTCC细胞库

Name细胞名称：NTCC® AG08526 ALZHEIMER DISEASE; AD B-Lymphocyte Cell Line
阿尔茨海默病；广告细胞株
Description描述：This donor was initially diagnosed as Parkinson's disease because he exhibited a slowing of movements. Within 1 year he developed problems with attention span and memory. Further progression of intellectual impairment necessitated assistance with all activities of daily living. Treatment with anti-Parkinsonian medications did not help motor or intellectual function. EEG revealed general slowing. CSF exam was remarkable for an increase in protein concentration. CT scan demonstrated widened sulci and ventricular dilatation. Autopsy confirmed Alzheimer's disease. The culture was initiated on 11/05/85 by transformation of lymphocytes with Epstein Barr virus. The cells grow in suspension and their morphology is spherical. The culture is a mosaic with karyotype: 45,XY,dic(13;19)(p11.3;q13.4)/46,XY; unbalanced; 8%/92% with 6% of the cells examined showing random chromosome loss and 12% showing random chromosomal aberrations. A skin fibroblast culture from same donor is AG08527A. The legacy karyotype description shown in this Remark may not be representative of the current available product.
Category分类：B-Lymphocyte
ID编号:NTCC®-AG08526
Size/Quantity数量: 1 Flask/2 Vials
Biosafety Level生物安全级别:1
Shipping Info运输方式: RT/Dry Ice
Storage储存方式: RT/Liquid Nitrogen
Race: White
Age年龄:61 YR
Gender性别:Male
Cell Type细胞类型: ALZHEIMER DISEASE; AD
Affected State:Yes
Product:LCL
Gene:
Mutations突变:
Ethnicity:GERMAN
Family:2051
Relationship:V-31
Karyotype:45,XY,dic(13;19)(p11.3;q13.4){8}/ 46,XY{92}
Tissue Type组织来源:Blood
Complete Growth Medium完全培养基: BioVector® Roswell Park Memorial Institute Medium 1640 with 2mM L-glutamine or equivalent Complete Medium
Subculturing传代方法:
Cryopreservation冻存方法:Freeze medium: Complete growth medium supplemented with 5% (v/v) DMSO
Storage temperature: liquid nitrogen vapor phase
Culture Conditions培养条件:Atmosphere: air, 95%; carbon dioxide (CO2), 5%
Temperature: 37.0°C
STR Profile鉴定数据:
References参考文献:

Supplier供应商:BioVector质粒载体菌株细胞蛋白抗体基因保藏中心
NTCC典型培养物保藏中心
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