GM10881色素性干皮病，补充组 C； XPC| XPC复合亚基、DNA损伤识别和修复因子； XPC成纤维细胞Cell Line细胞株-BioVector NTCC细胞库

Name细胞名称：NTCC® GM10881 XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP C; XPC | XPC COMPLEX SUBUNIT, DNA DAMAGE RECOGNITION AND REPAIR FACTOR; XPC Cell Line
色素性干皮病，补充组 C； XPC| XPC复合亚基、DNA损伤识别和修复因子； XPC细胞株
Description描述：XP1BE; 10-20% of normal UV induced unscheduled DNA synthesis; see GM02246 (lymphoblastoid); skin manifestations but no neurological abnormalities; developed freckles by age 2; 1st tumor at age 4; by age 28, over 100 neoplasma, including malignant melanomas, developed; corneal edema; the donor subject carries a deletion of the dinucleotide AA at positions 1132 and 1133 in the cDNA of the XPC gene, resulting in premature termination of the protein by a new stop codon 15 nucleotides downstream. The deletion may be either homozygous or hemizygous.
Category分类：Fibroblast
ID编号:NTCC®-GM10881
Size/Quantity数量: 1 Flask/2 Vials
Biosafety Level生物安全级别:1
Shipping Info运输方式: RT/Dry Ice
Storage储存方式: RT/Liquid Nitrogen
Race: White
Age年龄:45 YR
Gender性别:Female
Cell Type细胞类型: XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP C; XPC | XPC COMPLEX SUBUNIT, DNA DAMAGE RECOGNITION AND REPAIR FACTOR; XPC
Affected State:Yes
Product:Fibroblast
Gene:XPC
Mutations突变:2-BP DEL, 1132AA
Ethnicity:
Family:482
Relationship:proband
Karyotype:
Tissue Type组织来源:
Complete Growth Medium完全培养基: BioVector® Eagle's Minimum Essential Medium with Earle's salts and non-essential amino acids with 2mM L-glutamine or equivalent Complete Medium
Subculturing传代方法:
Cryopreservation冻存方法:Freeze medium: Complete growth medium supplemented with 5% (v/v) DMSO
Storage temperature: liquid nitrogen vapor phase
Culture Conditions培养条件:Atmosphere: air, 95%; carbon dioxide (CO2), 5%
Temperature: 37.0°C
STR Profile鉴定数据:
References参考文献:

Supplier供应商:BioVector质粒载体菌株细胞蛋白抗体基因保藏中心
NTCC典型培养物保藏中心
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