AG06929色素性干皮病，补充组 A； XPA 皮肤、手臂成纤维细胞Cell Line细胞株-BioVector NTCC细胞库

Name细胞名称：NTCC® AG06929 XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP A; XPA Skin, Arm Cell Line
色素性干皮病，补充组 A； XPA细胞株
Description描述：The Egyptian donor had features of freckled and pigmented skin on face, keratosis on the right cheek and carcinoma on the nose. Family history is negative, but parents are first cousins. The culture was initiated on 7/13/83 using explants of minced skin tissue from a biopsy taken earlier and stored frozen. The cell morphology is fibroblast-like. Complementation group assignment and DNA repair deficiency have been verified for this culture (XP23CA). The donor subject is homozygous for a C-to-T substitution at nucleotide 682 (682C>T) which alters the arg-228 codon (CGA) to a nonsense codon (TGA) in exon 6 of the XPA gene [ARG228TER (R228X)]. Culture grows slowly.
Category分类：Fibroblast
ID编号:NTCC®-AG06929
Size/Quantity数量: 1 Flask/2 Vials
Biosafety Level生物安全级别:1
Shipping Info运输方式: RT/Dry Ice
Storage储存方式: RT/Liquid Nitrogen
Race: White
Age年龄:18 YR
Gender性别:Female
Cell Type细胞类型: XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP A; XPA
Affected State:Yes
Product:Fibroblast
Gene:XPA
Mutations突变:ARG228TER
Ethnicity:EGYPTIAN
Family:
Relationship:proband
Karyotype:
Tissue Type组织来源:Skin
Complete Growth Medium完全培养基: BioVector® Eagle's Minimum Essential Medium with Earle's salts and non-essential amino acids with 2mM L-glutamine or equivalent Complete Medium
Subculturing传代方法:
Cryopreservation冻存方法:Freeze medium: Complete growth medium supplemented with 5% (v/v) DMSO
Storage temperature: liquid nitrogen vapor phase
Culture Conditions培养条件:Atmosphere: air, 95%; carbon dioxide (CO2), 5%
Temperature: 37.0°C
STR Profile鉴定数据:
References参考文献:

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