GM23418 CHARCOT-MARIE-TOOTH DISEASE; INHERITANCE UNKNOWN B-Lymphocyte Cell Line NTCC®细胞株-BioVector NTCC细胞库

Name细胞名称：NTCC® GM23418 CHARCOT-MARIE-TOOTH DISEASE; INHERITANCE UNKNOWN B-Lymphocyte Cell Line
夏科-玛丽-图斯病；继承权未知细胞株
Description描述：Clinically affected; symptom onset at age 38 years; diagnosis at age 39 years; _x000D_ numbness in arms and hands; loss of dexterity; mild hammertoes; high arched feet; wide, unsteady steppage gait; down going toes bilaterally; mild foot drop; tripping, especially with right foot; decreased pinprick sensation below the knees bilaterally; absent vibratory sensation in the toes bilaterally; decreased temperature sensation in the legs distally; mild weakness of foot dorsiflexion bilaterally; subject also has a history of: degenerative spinal cord compression; carpal tunnel syndrome; hyperthyroidism; depression and psoriatic arthritis; CMT diagnosed by nerve conduction velocity studies conducted at MDA clinic: evidence of sensorimotor polyneuropathy with predominantly demyelinating features and secondary axonal changes consistent with CMT; MRI of spine revealed evidence of myelomalacia at the C5-6 level; C6 cord compression; assistive devices include hand splints for carpel tunnel (worn inconsistently); surgeries include carpal tunnel release, shunt, cervical fusion, cervical laminectomy, lumbar drain, anterior cervical tissue graft; medications include Plaquenil, Methotrexate Sodium, Hydrocodone, Aleve/Excedrin, Flexeril, Sulfasalazine, Levothyroid, and Enbrel; father and sibling are also reported to be affected with CMT. _x000D_
Category分类：B-Lymphocyte
ID编号:NTCC®-GM23418
Size/Quantity数量: 1 Flask/2 Vials
Biosafety Level生物安全级别:1
Shipping Info运输方式: RT/Dry Ice
Storage储存方式: RT/Liquid Nitrogen
Race: White
Age年龄:55 YR
Gender性别:Female
Cell Type细胞类型: CHARCOT-MARIE-TOOTH DISEASE; INHERITANCE UNKNOWN
Affected State:Yes
Product:LCL
Gene:
Mutations突变:
Ethnicity:
Family:
Relationship:proband
Karyotype:
Tissue Type组织来源:Blood
Complete Growth Medium完全培养基: BioVector® Roswell Park Memorial Institute Medium 1640 with 2mM L-glutamine or equivalent Complete Medium
Subculturing传代方法:
Cryopreservation冻存方法:Freeze medium: Complete growth medium supplemented with 5% (v/v) DMSO
Storage temperature: liquid nitrogen vapor phase
Culture Conditions培养条件:Atmosphere: air, 95%; carbon dioxide (CO2), 5%
Temperature: 37.0°C
STR Profile鉴定数据:
References参考文献:

Supplier供应商:BioVector质粒载体菌株细胞蛋白抗体基因保藏中心
NTCC典型培养物保藏中心
Tel电话：400-800-2947
Email：Biovector@163.com
http://www.biovector.net