GM16147 CRICETULUS | X-RAY REPAIR, COMPLEMENTING DEFECTIVE, IN CHINESE HAMSTER, 4; XRCC4 Gonad, Ovary Cell Line NTCC®细胞株-BioVector NTCC细胞库

Name细胞名称：NTCC® GM16147 CRICETULUS | X-RAY REPAIR, COMPLEMENTING DEFECTIVE, IN CHINESE HAMSTER, 4; XRCC4 Gonad, Ovary Cell Line
仓鼠 | X 射线修复，补充缺陷，中国仓鼠，4； XRCC4细胞株
Description描述：Line XR-1; Chinese hamster ovary fibroblast line derived from cell line 4364 which is a proline, glycine-deficient mutant isolated from CHO-K1. XR-1 has a unique cell cycle-dependent x-ray sensitivity, very sensitive G1 and early S, less sensitive in late S phase. Defective in the repair of DNA double strand breaks through the nonhomologous end joining mechanism and in V(D)J recombination where both conserved recognition sequence and coding sequence rejoining are affected. XR-1 is complemented by the human XRCC (x-ray cross complementing) 4 gene, located on 5q13-14. HuXRCC4 encodes a ubiquitously expressed 38KDa protein unrelated to any described protein. Both XRCC4 copies are deleted in XR-1. XRCC4 protein forms a complex with and stimulates DNA ligase IV activity.
Category分类：Fibroblast
ID编号:NTCC®-GM16147
Size/Quantity数量: 1 Flask/2 Vials
Biosafety Level生物安全级别:1
Shipping Info运输方式: RT/Dry Ice
Storage储存方式: RT/Liquid Nitrogen
Race:
Age年龄:
Gender性别:
Cell Type细胞类型: CRICETULUS | X-RAY REPAIR, COMPLEMENTING DEFECTIVE, IN CHINESE HAMSTER, 4; XRCC4
Affected State:
Product:Fibroblast
Gene:FLNA RYR1
Mutations突变:c.2039C>T p.Q1589P
Ethnicity:
Family:
Relationship:proband
Karyotype:
Tissue Type组织来源:Gonad
Complete Growth Medium完全培养基: BioVector® Ham's F12 with 2mM L-glutamine or equivalent Complete Medium
Subculturing传代方法:
Cryopreservation冻存方法:Freeze medium: Complete growth medium supplemented with 5% (v/v) DMSO
Storage temperature: liquid nitrogen vapor phase
Culture Conditions培养条件:Atmosphere: air, 95%; carbon dioxide (CO2), 5%
Temperature: 37.0°C
STR Profile鉴定数据:
References参考文献:

Supplier供应商:BioVector质粒载体菌株细胞蛋白抗体基因保藏中心
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