GM00449 FANCONI ANEMIA, COMPLEMENTATION GROUP C; FANCC | FANCC GENE; FANCC Cell Line NTCC®细胞株-BioVector NTCC细胞库

Name细胞名称：NTCC® GM00449 FANCONI ANEMIA, COMPLEMENTATION GROUP C; FANCC | FANCC GENE; FANCC Cell Line
FANCONI 贫血，补充组 C； FANCC| FANCC基因； FACC细胞株
Description描述：Clinically affected; complementation group C; pancytopenia; classical symptoms; increased incidence of chromatid breaks and gaps following x-irradiation during G2; low-normal NAD+ levels in cells: 973 +/- 454 pmol/million cells (mean for normal cells = 1,140 +/- 304 pmol/million cells); donor subject is homozygous for a splice site mutation [IVS4+4A>T] in the FANCC gene in which a single base change in the fourth intronic base changes the sequence from a consensus A to T, resulting in deletion of the 111-bp exon 4; see GM13136 SV40 Transformed Fibroblast._x000D_
Category分类：Fibroblast
ID编号:NTCC®-GM00449
Size/Quantity数量: 1 Flask/2 Vials
Biosafety Level生物安全级别:1
Shipping Info运输方式: RT/Dry Ice
Storage储存方式: RT/Liquid Nitrogen
Race: White
Age年龄:6 YR
Gender性别:Female
Cell Type细胞类型: FANCONI ANEMIA, COMPLEMENTATION GROUP C; FANCC | FANCC GENE; FANCC
Affected State:Yes
Product:Fibroblast
Gene:FANCC
Mutations突变:IVS,A>T,+4
Ethnicity:
Family:1578
Relationship:proband
Karyotype:46,XX,add(13)(q34)[2]/46,XX,add(21)(q22)[2]/46,XX[15]
Tissue Type组织来源:Skin
Complete Growth Medium完全培养基: BioVector® Eagle's Minimum Essential Medium with Earle's salts and non-essential amino acids with 2mM L-glutamine or equivalent Complete Medium
Subculturing传代方法:
Cryopreservation冻存方法:Freeze medium: Complete growth medium supplemented with 5% (v/v) DMSO
Storage temperature: liquid nitrogen vapor phase
Culture Conditions培养条件:Atmosphere: air, 95%; carbon dioxide (CO2), 5%
Temperature: 37.0°C
STR Profile鉴定数据:
References参考文献:

Supplier供应商:BioVector质粒载体菌株细胞蛋白抗体基因保藏中心
NTCC典型培养物保藏中心
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