GM23742 AMYOTROPHIC LATERAL SCLEROSIS 1; ALS1 B-Lymphocyte Cell Line NTCC®细胞株-BioVector NTCC细胞库

Name细胞名称：NTCC® GM23742 AMYOTROPHIC LATERAL SCLEROSIS 1; ALS1 B-Lymphocyte Cell Line
肌萎缩侧索硬化症 1；肌萎缩侧索硬化症1细胞株
Description描述：Clinically affected; onset of symptoms at age 54 years; difficulty swallowing; dysphonia; atrophy/weakness of tongue and facial muscles; fasciculations involving the extremities; bilateral brisk reflexes; absence of any sensory findings; shortness of breath; EMG nerve conduction studies revealed: reduced sensory nerve action potential amplitudes of bilateral median nerves with prolonged latencies, markedly prolonged distal motor latencies of bilateral median nerves with reduced to borderline normal CMAP amplitudes; conduction velocity proximally is borderline normal to slightly slowed, absent right median and ulnar F-responses while right posterior tibial F-response latency is significantly prolonged, left median F response latency is very much prolonged; needle electromyography results revealed fasciculation potentials in the majority of muscles sampled, increased proportion of high amplitude, long duration, polyphasic units with reduced recruitment pattern, APB muscles reveal disproportionately more denervation; possible coexisting neuropathy, polyradiculopathy in addition to ALS considered due to presence of abnormal sensory nerve conduction velocities and more severely reduced velocities and conduction velocities; subject uses communication/learning device and speech, occupational and physical therapy; positive family history: mother, aunt and first cousin were also affected (not in repository).
Category分类：B-Lymphocyte
ID编号:NTCC®-GM23742
Size/Quantity数量: 1 Flask/2 Vials
Biosafety Level生物安全级别:1
Shipping Info运输方式: RT/Dry Ice
Storage储存方式: RT/Liquid Nitrogen
Race: More than one race
Age年龄:56 YR
Gender性别:Male
Cell Type细胞类型: AMYOTROPHIC LATERAL SCLEROSIS 1; ALS1
Affected State:Yes
Product:LCL
Gene:
Mutations突变:
Ethnicity:AMERICAN INDIAN/CAUCASIAN
Family:
Relationship:proband
Karyotype:
Tissue Type组织来源:Blood
Complete Growth Medium完全培养基: BioVector® Roswell Park Memorial Institute Medium 1640 with 2mM L-glutamine or equivalent Complete Medium
Subculturing传代方法:
Cryopreservation冻存方法:Freeze medium: Complete growth medium supplemented with 5% (v/v) DMSO
Storage temperature: liquid nitrogen vapor phase
Culture Conditions培养条件:Atmosphere: air, 95%; carbon dioxide (CO2), 5%
Temperature: 37.0°C
STR Profile鉴定数据:
References参考文献:

Supplier供应商:BioVector质粒载体菌株细胞蛋白抗体基因保藏中心
NTCC典型培养物保藏中心
Tel电话：400-800-2947
Email：Biovector@163.com
http://www.biovector.net