HCT 116 CDK2 (D145N/+)癌细胞株NTCC® Cancer cell line细胞株/完全培养基-BioVector NTCC典型培养物保藏中心

[Designation名称] NTCC® ID HCT 116 CDK2 (D145N/+) Cell Line细胞株
BioVector NTCC Inc.

DR cancercelllines; CVCL_LD87
DR Horizon_Discovery; HD+104-029
SY CDK2 (D145N/+) HCT116
DR Wikidata; Q54881924
CC Population: Caucasian.
CC Characteristics: Heterozygous knockin of a CDK2 dominant negative mutation.
CC Sequence variation: Mutation; HGNC; 173; ACVR2A; Simple; p.Lys437Argfs*5 (c.1310delA); dbSNP=rs764719749; Zygosity=Homozygous (from parent cell line).
CC Sequence variation: Mutation; HGNC; 1101; BRCA2; Simple; p.Ile2675Aspfs*6 (c.8021dupA) (c.8021_8022insA); ClinVar=VCV000267050; Zygosity=Heterozygous (from parent cell line).
CC Sequence variation: Mutation; HGNC; 1771; CDK2; Simple_edited; p.Asp145Asn; Zygosity=Heterozygous; Note=By method not specified (Horizon_Discovery=HD+104-029).
CC Sequence variation: Mutation; HGNC; 1787; CDKN2A; Simple; p.Arg24Serfs*20 (c.68dupG) (c.68_69insG) (p.G23fs); Zygosity=Heterozygous (from parent cell line).
CC Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Heterozygous (from parent cell line).
CC Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
CC Sequence variation: Mutation; HGNC; 11773; TGFBR2; Simple; p.Lys128Serfs*35 (c.383delA); ClinVar=VCV000477546; Zygosity=Homozygous (from parent cell line).
[Organism物种来源]
[Disease疾病种类]
[Accession编号] NTCC®-AC CVCL_LD87
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[Reference参考文献]
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[Date保藏时间]
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培养方法：
Medium培养基：NTCC® ID HCT 116 CDK2 (D145N/+) Complete Medium
Growth properties形态：贴壁/悬浮：
Culture Condition培养条件：Temperature温度: 37°C.
Atmosphere: 95% Air, 5% CO2

Supplier生产厂家: BioVector NTCC质粒载体菌种细胞蛋白抗体基因保藏中心
Website网址：www.biovector.net