U2OS GLP1R cAMP-Nomad Cancer cell line NTCC®细胞株/完全培养基-BioVector NTCC典型培养物保藏中心

[Designation名称] NTCC® U2OS GLP1R cAMP-Nomad Cell Line细胞株
BioVector NTCC Inc.

Cross-references: Innoprot; P70503
Cross-references: Wikidata; Q98133746
Synonyms: GLP1R cAMP-Nomad; GLP1R Nomad; cAMPNomad-GLP1R
Comments: Population: Caucasian.
Comments: Characteristics: In absence of cAMP, the fluorescent biosensor is localized in the cellular membrane. An increase in this second messenger concentration leads to change in the structural folding of Nomad biosensor that promotes its cellular relocation in the vesicular trafficking of the cells.
Comments: Characteristics: The red cAMP-Nomad biosensor consists of a membrane localization peptide derived from interleukin-2 receptor alpha chain, a TurboFP650 fluorescent protein, a Ht31 peptide fused to a KDEL signal.
Comments: Sequence variation: Mutation; HGNC; 9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
Comments: Transfected with: HGNC; 4324; GLP1R.
Comments: Transfected with: UniProtKB; J9PBR7; Entacmaea quadricolor far-red fluorescent protein eqFP650.
Comments: Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Comments: Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
Comments: Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Diseases: NCIt; C9145; Osteosarcoma
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[Accession编号] NTCC® Accession: NTCC_YK45
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培养方法：
Medium培养基：NTCC® Specific Complete Medium
Growth properties形态：贴壁/悬浮：
Culture Condition培养条件：Temperature温度: 37°C.
Atmosphere: 95% Air, 5% CO2

Supplier生产厂家: BioVector NTCC质粒载体菌种细胞蛋白抗体基因保藏中心
Website网址：www.biovector.net