MCF7-LTED cell line耐药细胞株 BioVector NTCC质粒载体菌种细胞基因保藏中心

MCF7-LTED cell line耐药细胞株

Cell line name MCF7-LTED
Synonyms MCF7 LTED; LTED-I; MCF7-Long Term Estrogen-Deprived
Accession NTCC®_YX84
Resource Identification Initiative To cite this cell line use: MCF7-LTED (NTCC®_YX84)
Comments Population: Caucasian.
Characteristics: Derived from parent cell line by long-term culture in the presence of RPMI-1640 medium containing 10% dextran charcoal stripped serum (DCC) (PubMed=26116361).
Sequence variations
Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: NTCC®_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line

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