P2RY6 gene基因表达质粒敲除编辑载体 BioVector NTCC质粒载体菌种细胞基因保藏中心

P2RY6 gene基因表达质粒敲除编辑载体

RefSeq NM_176797.2
RefSeq Size 1555 bp
RefSeq ORF 987 bp
Locus ID 5031
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Neuroactive ligand-receptor interaction
Gene Summary The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, which is a G-protein coupled receptor, is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. It is proposed that this receptor mediates inflammatory responses. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

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