HEK293/MC4R cell line稳转表达细胞株 BioVector NTCC质粒载体菌种细胞基因保藏中心

HEK293/MC4R cell line稳转表达细胞株

Melanocortin receptor-4 (MC4R) gene mutations are associated with early-onset severe obesity, and the identification of potential pathological variants is crucial for the clinical management of patients with obesity.
In vitro experiments showed that HEK293 cells transfected with the mutated form of MC4R did not increase intracellular cAMP or Ca2+ levels .

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