Adeno Associated Virus (AAV) Control Virus (GFP,RFP,luciferase)腺相关病毒荧光对照 BioVector NTCC质粒载体菌种细胞基因保藏中心

Adeno Associated Virus (AAV) Control Virus (GFP,RFP,luciferase)腺相关病毒荧光对照

Adeno associated virus (AAV) is one kind of human parvovirus. Recombinant AAV vectors can efficiently transfect various cell types, including dividing and quiescent cells, and induce persistent gene expression in vivo without integrating into host genome and causing any disease. These features make AAV an attractive candidate in the application of gene delivery for gene therapy and human disease model establishment. To date, AAV has been proved as the most excellent gene therapy vector. Over 204 clinical trials have been carried out using AAV vectors for gene delivery, and promising gene therapy outcomes have been achieved from clinical trials for a great number of diseases.
Genemedi has launched a comprehensive AAV production service. More than 12 AAV serotypes and a variety of capsid engineered AAV vectors are available for targeting different tissues and organs. The engineered AAV serotypes with modification of AAV capsids contain AAV PHP.B, AAV-PHP.eB, AAV PHP.s, AAV-retro, AAV-Anc80 (L65), AAV DJ, AAVDJ8, and some other specific AAV serotypes not mentioned.
Based on these engineered AAV serotypes, a variety of AAV control viruses with different fluorescent labels (such as GFP, RFP, YFP and so on), and various promoters (such as CMV, CAG, syn, TBG and cTNT etc.) or peptide tags, are packaged as premade or customized virus for customers .
AAV serotypes and their respective Tropism
AAV SErotype Tissue tropism
CNS Retina Lung Liver Pancreas Kidney Heart Muscle
AAV1 √ √   √  √ √
AAV2  √  √  √  
AAV3  √ √ √   √
AAV4 √ √     √
AAV5 √ √ √  √  
AAV6 √  √ √   √ √
AAV7    √    √
AAV8  √  √ √   √
AAV9 √  √ √   √ √
AAV-DJ  √ √ √  √  
AAV-DJ/8  √  √    √
AAV-Rh10 √  √ √   √ √
AAV-retro √ √      √
AAV-PHP.B √      √ √
AAV8-PHP.eB √       √
AAV-PHP.S √      √ √

Adeno Associated Virus (AAV) related products and service
 Pre-made Adeno Associated Virus (AAV) Products
AAV Vector System in Multi-serotypes
Pre-made Optogenetics AAV
Promise-ORFTM Pre-made AAV
Pre-made CRISPR/Cas9 AAV
Pre-made AAV-LC3 Autophagy Flux Biosensor
Control Pre-made AAV
Multi-serotypes of AAV Cre-loxP system
Pre-made AAV biosensors

 Custom Adeno Associated Virus (AAV) service
Custom-made AAV Production
Custom-made Optogenetics AAV
Custom-made CRISPR/Cas9-gRNA AAV
Control AAV Service
AAV Capsids Evolution Service

 Adeno Associated Virus (AAV) Vector System
AAV Vector System in Multi-serotypes
AAV Rep-Cap Plasmids in Multi-serotypes
AAV Expression Vector with Multi-promoters

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Website网址: http://www.biovector.net