Canine hemangiopericytoma (CHP) cell line细胞株 BioVector NTCC质粒载体菌种细胞基因保藏中心
- 价 格:¥498685
- 货 号:Canine hemangiopericytoma (CHP)
- 产 地:北京
- BioVector NTCC典型培养物保藏中心
- 联系人:Dr.Xu, Biovector NTCC Inc.
电话:400-800-2947 工作QQ:1843439339 (微信同号)
邮件:Biovector@163.com
手机:18901268599
地址:北京
- 已注册
Canine hemangiopericytoma (CHP) cell line细胞株
BioVector® AAV-PHP.eB Rep-Cap plasmid (specific serotype across (blood-brain barrier(BBB) AAV RC plamid), also named AAV-PHP.eB RC plasmid,is part of AAV-PHP.eB packaging system. AAV-PHP.eB Rep-Cap plamid supplies the AAV2 Rep(replication) proteins and the AAV-PHP.eB capsid protein.
You can produce AAV-PHP.eB paticle in 293T cell line in high titer using GeneMedi's AAV-PHP.eB Rep-Cap plasmid with GeneMedi's AAV expression vector(overexpression or shRNA) and AAV helper plasmid.
AAV-PHP.eB (also called AAV9-PHP.eB) is a variant from AAV9 with AAV capsid evolution (AAV capsid peptide display). With enhanced CNS tropism (neurotropic),the AAV-PHP.eB variant vector has also been validated in gene delivery in vivo across the blood-brain barrier(BBB) following intravenous infusion.LY6A, a novel cellular receptor has been verified as an essential receptor for AAV-PHP.eB vector.
With the blood-brain barrier(BBB) crossing propertiy,AAV-PHP.eB shows potential applications in CNS (neuron) gene therapy,especially in neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD),or neurogenetic disease such as Spinal Muscular Atrophy (SMA) and Huntington's disease(HD).
Supplier来源:BioVector NTCC Inc.
TEL电话:400-800-2947
Website网址: http://www.biovector.net
- 公告/新闻