SKBR3-TR Trastuzumab Resistant Human Breast Cancer Cell Line曲妥珠单抗耐药人乳腺癌细胞株 BioVector NTCC质粒载体菌种细胞基因保藏中心

SKBR3-TR Trastuzumab Resistant Human Breast Cancer Cell Line曲妥珠单抗耐药人乳腺癌细胞株

Cell line name SKBR3-TR

Comments  Population: Caucasian.
Selected for resistance to: DrugBank; DB00072; Trastuzumab (Herceptin).

Sequence variations
Gene deletion; HGNC; 1748; CDH1; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Homozygous (from parent cell line).

Disease Breast adenocarcinoma (NCIt: C5214)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: (SK-BR-3)

Sex of cell Female
Age at sampling 43Y
Category Cancer cell line

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