GCN2 gene (EIF2AK4) 基因表达质粒敲除编辑载体 BioVector NTCC质粒载体菌种细胞基因保藏中心
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GCN2 gene (EIF2AK4) 基因表达质粒敲除编辑载体
RefSeq NM_001013703.2, NP_001013725.2RefSeq Size 5532 bpRefSeq ORF 4950 bpLocus ID 440275Protein Families Druggable Genome, Protein KinaseMW 187.4 kDaGene Summary This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2.
Supplier来源:BioVector NTCC Inc.
TEL电话:400-800-2947
Website网址: http://www.biovector.net
RefSeq NM_001013703.2, NP_001013725.2RefSeq Size 5532 bpRefSeq ORF 4950 bpLocus ID 440275Protein Families Druggable Genome, Protein KinaseMW 187.4 kDaGene Summary This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2.
Supplier来源:BioVector NTCC Inc.
TEL电话:400-800-2947
Website网址: http://www.biovector.net
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