首页 » GCN2 gene (EIF2AK4) 基因表达质粒敲除编辑载体 BioVector NTCC质粒载体菌种细胞基因保藏中心

GCN2 gene (EIF2AK4) 基因表达质粒敲除编辑载体 BioVector NTCC质粒载体菌种细胞基因保藏中心

  • 价  格:¥49865
  • 货  号:GCN2
  • 产  地:北京
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GCN2 gene (EIF2AK4) 基因表达质粒敲除编辑载体

RefSeq NM_001013703.2, NP_001013725.2
RefSeq Size 5532 bp
RefSeq ORF 4950 bp
Locus ID 440275
Protein Families Druggable Genome, Protein Kinase
MW 187.4 kDa
Gene Summary This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2.

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