K562/IL-21 cell line细胞株 BioVector NTCC质粒载体菌种细胞基因保藏中心

K562/IL-21 cell line细胞株

K562-based aAPCs with membrane-bound IL-21 (mbIL21).
mbIL21-expressing aAPCs promoted log-phase NK cell expansion without evidence of senescence for up to 6 weeks of culture. Despite the significant increase in proliferation, mbIL21-expanded NK cells also showed a significant increase in telomere length compared to freshly obtained NK cells, suggesting a possible mechanism for their sustained proliferation.

Organism: Homo sapiens, human
Tissue: bone marrow
Disease: chronic myelogenous leukemia (CML)
Age: 53 years
Gender: female
Morphology: lymphoblast
Growth Properties: suspension
Isoenzymes:
AK1,
1
ESD,
1
G6PD, B
GLOI,
2
Me2,
0
PGM1, 0
PGM3, 1

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