pFUSEN-hG1e2Fc质粒载体-BioVector质粒保藏中心

Name质粒名称:pFUSEN-hG1e2Fc
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Description描述:Fc-fusion protein expression plasmid - Engineered human IgG1 pFUSEN-hG1e2Fc is a cloning plasmid for the generation of a Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the mutated human IgG1 heavy chain and the hinge region fused to the N-terminus of a protein of interest.. The engineered hIgG1e2 Fc contains the following mutations: M252Y/S254T/T256E and H433K/N434F. Human IgG1e2-Fc contains mutations in the site of interaction of IgG1 with FcRn that enhance the plasma half-life by increasing the affinity of IgG1 for FcRn. Back to the top Specifications Isotype: IgG1 human Mutations: M252Y/S254T/T256E + H433K/N434F Characteristics: - Increased binding to neonatal FcR (FcRn) - Increased half-life Selectable with Zeocin™ in E. coli and mammalian cells. For transient or stable transfection. Back to the top pFUSEN Contents 20 µg of lyophilized DNA 1 ml of Zeocin™ (100 mg/ml) room temperature Product is shipped at room temperature Back to the top Details pFUSEN-Fc map
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