首页 » pNZ8048-hGH人生长激素乳酸菌表达质粒 BioVector NTCC质粒载体菌种细胞基因保藏中心

pNZ8048-hGH人生长激素乳酸菌表达质粒 BioVector NTCC质粒载体菌种细胞基因保藏中心

  • 价  格:¥98965
  • 货  号:pNZ8048-hGH
  • 产  地:北京
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pNZ8048-hGH人生长激素乳酸菌表达质粒

pNZ8048 Plasmid information

Promoter: PnisA
Replicon: repA, repC
Terminator: Terminator
Plasmid classification: secreted expression plasmid of Lactobacillus
Plasmid size: 3349bp
Prokaryotic resistance: chloramphenicol chloramphenicol
Screening marker: chloramphenicol chloramphenicol
Clone strain: MC1061
Culture conditions: 37, aerobic, LB
Expressing host: Lactobacillus
Primers for 5'sequencing: Based on sequence design

GH1 growth hormone 1 [ Homo sapiens (human) ]
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.

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