SK-BR-3人乳腺腺癌细胞株-BioVector NTCC典型培养物保藏中心

SK-BR-3人乳腺腺癌细胞株

BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心

SK-BR-3: A Model for HER2-Positive Breast Cancer

SK-BR-3 is a human breast cancer cell line that overexpresses the HER2 (human epidermal growth factor receptor 2) gene.

SKBR3 cells

Why is the SK-BR-3 cell line important?

This cell line is a valuable tool for studying:

• HER2-positive breast cancer: Understanding the molecular mechanisms underlying the aggressive nature of HER2-positive tumors.

• Drug discovery and development:Screening potential therapeutic agents targeting HER2, such as trastuzumab (Herceptin).

  
  

• Mechanisms of drug resistance:Investigating how cancer cells develop resistance to HER2-targeted therapies.

  
  

• Tumor biology:Studying tumor cell proliferation, invasion, and metastasis.

  
  

Key characteristics of SK-BR-3 cells:

• HER2 overexpression: High levels of HER2 protein expression on the cell surface.

  
  

• Aggressive phenotype: Rapid growth and metastatic potential.

  
  

• Sensitivity to HER2-targeted therapies: Responsive to treatments that target the HER2 signaling pathway.

By studying SK-BR-3 cells, researchers can gain valuable insights into the biology of HER2-positive breast cancer and develop more effective treatments for patients with this aggressive form of the disease.

   【中文名称】：    人乳腺腺癌细胞    【保藏编号】：    TCHu225    【来源】：    人    

【供应机构】：

BioVector NTCC典型培养物保藏中心

www.biovector.net