SNU16 (MYC- and FGFR2-amplified) BioVector NTCC质粒载体菌种细胞基因保藏中心
- 价 格：¥49865
- 货 号：SNU16 (MYC- and FGFR2-amplified)
- 产 地：北京
- BioVector NTCC典型培养物保藏中心
- 联系人：Dr.Xu, Biovector NTCC Inc.
电话：400-800-2947 工作微信:1843439339 (QQ同号)
邮件：Biovector@163.com
手机：18901268599
地址：北京
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SNU16 (MYC- and FGFR2-amplified)
SNU-16Cat#:BioVector-CRL-5974Product categoryHuman cellsOrganismHomo sapiens, humanMorphologyepithelialTissueStomachDiseaseGastric CarcinomaApplications3D cell cultureCancer researchGrowth propertiesSuspension, multicellular aggregatesDerivationSNU-16 was line derived in 1987 by J. Park and associates from ascites of a patient with poorly differentiated carcinoma of the stomach. The line was established from cells taken prior to chemotherapy. Age33 yearsEthnicityAsianGenderFemaleClinical dataThe line was established from cells taken prior to chemotherapy.KaryotypeThis is a human cell line with the bimodal chromosome number distributions. Both modal populations were hypotetraploid. Cells with higher ploidies occurred at 1%. Nine marker chromosomes were common to all cells: t(4q21q); der(5)t(2;5) (q11.2;q13); i(5p); del(17) (p11.2); del(10) (q22.1) and four others. Of these, del(17) generally had two copies per cell. Seven or more other marker chromosomes including HSR(11) (p15.1) were found in some cells only. Multiple copies of DMs were present in most cells. Consistently there were three normal X chromosomes per cell. N7 had six copies and N14, five copies per cell. Normal N12 was not found.TumorigenicYes, the cells have a reported colony forming efficiency of 10% in semisolid medium.; myc+; erb-B2+MetastaticAscitesAntigen expressionBlood Type A; Rh +The cells express the surface glycoproteins carcinoembryonic antigen (CEA) and TAG 72.Genes expressedmyc+; erb B2+; Rh+; carcinoembryonic antigen (CEA); TAG 72; blood type AExpression markersVasoactive intestinal peptide (VIP), expressedCommentsSNU-16 cells were positive for VIP receptors but lacked gastrin receptors.The line was established from cells taken prior to chemotherapy.No evidence of amplification or rearrangements was noted in the N-myc, L-myc, myb and EGF receptor genes. The c-myc proto-oncogene was apmplified, but expressed c-erb-B-2 RNA that were comparable to other cell lines. There was no expression of the following genes: N-myc, L-myc, c-cis, IGF-2, or gastrin releasing peptide.The cells express the surface glycoproteins carcinoembryonic antigen (CEA) and TAG-72. The cells are L-dopa decarboxylase (DDC) positive.Complete mediumThe base medium for this cell line is RPMI-1640 Medium. To make the complete growth medium, add the following components to the base medium: fetal bovine serum (ATCC 30-2020) to a final concentration of 10%.Temperature37°CAtmosphere95% Air, 5% CO2
Supplier来源:BioVector NTCC Inc.
TEL电话:+86-010-53513060
Website网址: http://www.biovector.net
SNU-16Cat#:BioVector-CRL-5974Product categoryHuman cellsOrganismHomo sapiens, humanMorphologyepithelialTissueStomachDiseaseGastric CarcinomaApplications3D cell cultureCancer researchGrowth propertiesSuspension, multicellular aggregatesDerivationSNU-16 was line derived in 1987 by J. Park and associates from ascites of a patient with poorly differentiated carcinoma of the stomach. The line was established from cells taken prior to chemotherapy. Age33 yearsEthnicityAsianGenderFemaleClinical dataThe line was established from cells taken prior to chemotherapy.KaryotypeThis is a human cell line with the bimodal chromosome number distributions. Both modal populations were hypotetraploid. Cells with higher ploidies occurred at 1%. Nine marker chromosomes were common to all cells: t(4q21q); der(5)t(2;5) (q11.2;q13); i(5p); del(17) (p11.2); del(10) (q22.1) and four others. Of these, del(17) generally had two copies per cell. Seven or more other marker chromosomes including HSR(11) (p15.1) were found in some cells only. Multiple copies of DMs were present in most cells. Consistently there were three normal X chromosomes per cell. N7 had six copies and N14, five copies per cell. Normal N12 was not found.TumorigenicYes, the cells have a reported colony forming efficiency of 10% in semisolid medium.; myc+; erb-B2+MetastaticAscitesAntigen expressionBlood Type A; Rh +The cells express the surface glycoproteins carcinoembryonic antigen (CEA) and TAG 72.Genes expressedmyc+; erb B2+; Rh+; carcinoembryonic antigen (CEA); TAG 72; blood type AExpression markersVasoactive intestinal peptide (VIP), expressedCommentsSNU-16 cells were positive for VIP receptors but lacked gastrin receptors.The line was established from cells taken prior to chemotherapy.No evidence of amplification or rearrangements was noted in the N-myc, L-myc, myb and EGF receptor genes. The c-myc proto-oncogene was apmplified, but expressed c-erb-B-2 RNA that were comparable to other cell lines. There was no expression of the following genes: N-myc, L-myc, c-cis, IGF-2, or gastrin releasing peptide.The cells express the surface glycoproteins carcinoembryonic antigen (CEA) and TAG-72. The cells are L-dopa decarboxylase (DDC) positive.Complete mediumThe base medium for this cell line is RPMI-1640 Medium. To make the complete growth medium, add the following components to the base medium: fetal bovine serum (ATCC 30-2020) to a final concentration of 10%.Temperature37°CAtmosphere95% Air, 5% CO2
Supplier来源:BioVector NTCC Inc.
TEL电话:+86-010-53513060
Website网址: http://www.biovector.net
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