首页 » EGF高效表达质粒/菌株Human epidermal growth factor (EGF) BioVector NTCC质粒载体菌种细胞基因保藏中心

EGF高效表达质粒/菌株Human epidermal growth factor (EGF) BioVector NTCC质粒载体菌种细胞基因保藏中心

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  • 货  号:EGF高效表达质粒菌株
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EGF高效表达质粒/菌株Human epidermal growth factor (EGF)

Human epidermal growth factor (EGF)

Synonyms HOMG4; URG
RefSeq NM_001963.2, NP_001954.1
RefSeq Size 5600 bp
RefSeq ORF 3624 bp
Locus ID 1950
Domains ldl_recept_b, EGF_CA, EGF, EGF
Protein Families Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transmembrane
Protein Pathways Bladder cancer, Cytokine-cytokine receptor interaction, Endocytosis, Endometrial cancer, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, MAPK signaling pathway, Melanoma, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Prostate cancer, Regulation of actin cytoskeleton
MW 133.9 kDa
Gene Summary This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.

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