CHO-K1/Tim3 cell line稳转细胞株 BioVector NTCC质粒载体菌种细胞基因保藏中心

CHO-K1/Tim3 cell line稳转细胞株

Description
T cell immunoglobulin mucin-3 (TIM-3) is a member of the T-cell Immunoglobulin- and Mucin-domain-containing family of type I membrane glycoproteins that regulate autoimmune and allergic disease. TIM-3 is selectively expressed on Th1 cells and interacts with galectin-9. It negatively regulates Th1 responses and affects macrophage activation. The 280 amino acid mature human TIM-3 contains a V-type Ig-like domain that shows multiple polymorphisms, followed by a mucin-like domain in the 171 amino acid extracellular region, which shares 60% amino acid identity with mouse TIM-3 ECD.

Synonyms
HAVCR2 ; CD366; HAVcr-2; KIM-3; TIM3; TIMD-3; TIMD3

Species Human
Freeze Medium 95% complete growth medium, 5% DMSO
Culture Medium F12K, 10% FBS, 8μg/ml Puromycin
Properties
Storage Liquid nitrogen immediately upon receiving
Applications
Binding assay or use as immunogen

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