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CHO-K1/PD-1
DescriptionProgrammed cell death protein 1, also known as PD-1 and CD279 (cluster of differentiation 279), is a protein that in humans is encoded by the PDCD1 gene. PD-1, functioning as an immune checkpoint, plays an important role in down regulating the immune system by preventing the activation of T-cells, which in turn reduces autoimmunity and promotes self-tolerance. The inhibitory effect of PD-1 is accomplished through a dual mechanism of promoting apoptosis (programmed cell death) in antigen specific T-cells in lymph nodes while simultaneously reducing apoptosis in regulatory T cells (suppressor T cells).SynonymsPDCD1 ; CD279; PD-1; SLEB2; hPD-1; hPD-l; hSLE1Species HumanFreeze Medium 95% Culture Medium, 5% (V/V) DMSOCulture Medium F12K, 10% FBS, 8 μg/ml PuromycinProperties Stability 15 passagesStorage Liquid nitrogen immediately upon receivingApplications Binding assay or use as immunogen
Supplier来源:BioVector NTCC Inc.
TEL电话:+86-010-53513060
Website网址: http://www.biovector.net
DescriptionProgrammed cell death protein 1, also known as PD-1 and CD279 (cluster of differentiation 279), is a protein that in humans is encoded by the PDCD1 gene. PD-1, functioning as an immune checkpoint, plays an important role in down regulating the immune system by preventing the activation of T-cells, which in turn reduces autoimmunity and promotes self-tolerance. The inhibitory effect of PD-1 is accomplished through a dual mechanism of promoting apoptosis (programmed cell death) in antigen specific T-cells in lymph nodes while simultaneously reducing apoptosis in regulatory T cells (suppressor T cells).SynonymsPDCD1 ; CD279; PD-1; SLEB2; hPD-1; hPD-l; hSLE1Species HumanFreeze Medium 95% Culture Medium, 5% (V/V) DMSOCulture Medium F12K, 10% FBS, 8 μg/ml PuromycinProperties Stability 15 passagesStorage Liquid nitrogen immediately upon receivingApplications Binding assay or use as immunogen
Supplier来源:BioVector NTCC Inc.
TEL电话:+86-010-53513060
Website网址: http://www.biovector.net
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