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Human Oral Keratinocytes HOK cell line人正常口腔角质细胞 BioVector NTCC质粒载体菌种细胞基因保藏中心

  • 价  格:¥99865
  • 货  号:HOK细胞
  • 产  地:北京
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Human Oral Keratinocytes HOK cell line人正常口腔角质细胞

Human Oral Keratinocytes
Human Primary Cells
Oral keratinocytes act as the major barrier to physical, microbial, and chemical agents that may cause local cell injury. They are involved in the proinflammatory process through the production of cytokines either constitutively or after a variety of stimuli, implying that they may potentially participate in controlling oral infections through an inflammatory process involving different interleukins, such as IL-1ß and IL-18. Oral keratinocytes express a variety of differentiation markers, the expression of which is influenced by calcium-induced changes in the transcription of target genes. Oral keratinocytes share major structural and functional features with the well-characterized dermal keratinocyte and provide a good model to study basic keratinocyte biology as well as processes of immortalization and malignant transformation.
HOK are isolated from human oral mucosa. HOK are cryopreserved at passage one and delivered frozen. Each vial contains >5 x 105 cells in 1 ml volume. HOK are characterized by immunofluorescence with antibodies specific to cytokeratine- 8, -18 and -19. HOK are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HOK are guaranteed to further expand for 10 population doublings under the conditions provided.

Recommended Medium: It is recommended to use Oral Keratinocyte Medium for the culturing of HOK in vitro.

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