UD-SCC-2 cell line细胞株 BioVector NTCC质粒载体菌种细胞基因保藏中心

UD-SCC-2 cell line细胞株

Cell line name UD-SCC-2
Synonyms UD-SCC 2; UD-SCC2; UDSCC-2; UDSCC2; University of Dusseldorf-Squamous Cell Carcinoma-2
Accession CVCL_E325
Resource Identification Initiative To cite this cell line use: UD-SCC-2 (RRID:CVCL_E325)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Part of: OPC-22 oral and pharyngeal cancer cell line panel.
Characteristics: Contains from 14 to 23 copies of the HPV16 genome.
Doubling time: 42 hours (PubMed=10628319); 4.1 days (PubMed=29156801).
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Omics: CNV analysis.
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: Genome sequenced (low read coverage).
Omics: Protein expression by reverse-phase protein arrays.
Omics: SNP array analysis.
Sequence variations Mutation; HGNC; 7133; KMT2D; Simple; p.Arg5154Gln (c.15461G>A); ClinVar=VCV000286834; Zygosity=Homozygous (PubMed=31541927).
Genome ancestry Source: PubMed=30894373

Origin % genome
African 3.2
Native American 0
East Asian, North 4
East Asian, South 0
South Asian 0
European, North 57.49
European, South 35.31
Disease Hypopharyngeal squamous cell carcinoma (NCIt: C4043)
Squamous cell carcinoma of the hypopharynx (ORDO: Orphanet_494547)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): PubMed=25275298; PubMed=29156801

Markers:
Amelogenin X,Y
CSF1PO 11,12
D3S1358 14,16
D5S818 10,11
D7S820 8,9
D8S1179 13,15
D13S317 8
D16S539 11,13
D18S51 12,17
D21S11 30,31.2
FGA 20,27
Penta D 9,13
Penta E 10
TH01 8,9
TPOX 8,10
vWA 15,18

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