ANBL6 BR BioVector NTCC质粒载体菌种细胞基因保藏中心

价　　格：¥99865
货　　号：ANBL6 BR
产　　地：北京

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ANBL6 BR

Cell line name ANBL-6 BR
Accession CVCL_QZ43
Resource Identification Initiative To cite this cell line use: ANBL-6 BR (RRID:CVCL_QZ43)
Comments Characteristics: Produces Ig lambda.
Characteristics: IL6 dependent.
Selected for resistance to: ChEBI; CHEBI:52717; Bortezomib (Velcade).
Derived from sampling site: Peripheral blood.
Sequence variations Mutation; HGNC; 12033; TRAF3; Simple; p.Tyr425Thrfs*36 (c.1272delC); Zygosity=Homozygous (from parent cell line).
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_5425 (ANBL-6)
Sex of cell Female
Age at sampling 67Y
Category Cancer cell line
Publications
PubMed=19344406; DOI=10.1111/j.1365-2141.2009.07647.x
Voorhees P.M., Chen Q., Small G.W., Kuhn D.J., Hunsucker S.A., Nemeth J.A., Orlowski R.Z.
Targeted inhibition of interleukin-6 with CNTO 328 sensitizes pre-clinical models of multiple myeloma to dexamethasone-mediated cell death.
Br. J. Haematol. 145:481-490(2009)

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