H929, 8226/I, RPMI8226 cell line细胞株 BioVector NTCC质粒载体菌种细胞基因保藏中心

H929, 8226/I, RPMI8226 cell line细胞株

Product category
Human cells
Organism
Homo sapiens
Cell type
B lymphocyte
Morphology
lymphoblast
Tissue
Bone; Marrow
Disease
Plasmacytoma
Applications
3D cell culture
Immune system disorder research
Immunology
Growth properties
Suspension
Derivation
This cell line was established from a malignant effusion in a patient with myeloma.
Age
62 years
Ethnicity
White
Gender
Female
Clinical data
This cell line was established from a malignant effusion.
Karyotype
Near tetraploid. Most copies of chromosome 8 have the 8q+ abnormality.
Antigen expression
PCA-1; CD38 +
Genes expressed
PCA-1; CD38+
Isotype
IgA, kappa
Comments
The cells are positive for plasma cell antigen 1 (PCA-1), transferrin receptor, CD38 (T10), but are negative for HLA DR, CALLA and markers of early B cell development.
They are negative for Epstein-Barr virus nuclear antigen (EBNA).
The cells have a rearrangement of the c-myc proto oncogene and express c-myc RNA.
There is also an activated ras allele.

Supplier来源:BioVector NTCC Inc.
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