酿酒酵母渗透敏感突变体fps1Δ BioVector NTCC质粒载体菌种细胞基因保藏中心

酿酒酵母渗透敏感突变体fps1Δ

Standard Name
FPS1
Systematic Name
YLL043W
SGD ID
SGD:S000003966
Feature Type
ORF , Verified
Description
Aquaglyceroporin, plasma membrane channel; involved in efflux of glycerol and xylitol, and in transport of acetate, arsenite, and antimonite; key factor in maintaining redox balance by mediating passive diffusion of glycerol; phosphorylated by Hog1p and Slt2p MAPK; deletion improves xylose fermentation; regulated by Rgc1p and Ask10p, which are regulated by Hog1p phosphorylation under osmotic stress; phosphorylation by Ypk1p required to maintain an open state
Name Description
fdp1 Suppressor
Protein
Basic sequence-derived (length, molecular weight, isoelectric point) and experimentally-determined (median abundance, median absolute deviation) protein information. Click "Protein Details" for further information about the protein such as half-life, abundance, domains, domains shared with other proteins, protein sequence retrieval for various strains, physico-chemical properties, protein modification sites, and external identifiers for the protein.
Length (a.a.)
669
Mol. Weight (Da)
73873.3
Isoelectric Point
6.9
Median Abundance (molecules/cell)
2264 +/- 862
Gene Ontology
GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code. SGD has manually curated and high-throughput GO Annotations, both derived from the literature, as well as computational, or predicted, annotations. Click "Gene Ontology Details" to view all GO information and evidence for this locus as well as biological processes it shares with other genes.
Summary
Glycerol channel involved in transport of glycerol, arsenite, acetate, and polyols; also involved in mating and the response to arsenic; localizes to the plasma membrane
Molecular Function
Manually Curated
·enables glycerol channel activity (IMP)
·enables glycerol transmembrane transporter activity (IDA, IMP)
Biological Process
Manually Curated
·involved in acetate transport (IMP)
·involved in arsenite transport (IMP)
·involved in conjugation with cellular fusion (IMP)
·involved in glycerol transport (IDA, IMP)
·involved in polyol transport (IMP)
Cellular Component
Manually Curated
·part of plasma membrane (IDA)
High-Throughput
·part of cell periphery (HDA)
·part of cytoplasm (HDA)
·part of fungal-type vacuole (HDA)
·part of plasma membrane (HDA)
Phenotype Details 
Phenotype
Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided. Click "Phenotype Details" to view all phenotype annotations and evidence for this locus as well as phenotypes it shares with other genes.

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