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MDA-T32 cell line细胞株
Cell line name MDA-T32 Comments Omics: Transcriptome analysis. Sequence variations Heterozygous for BRAF p.Val600Glu (c.1799T>A) (ClinVar=VCV000013961) (PubMed=23833040; PubMed=25427145; PubMed=30737244). Heterozygous for CDKN2A p.Leu78Hisfs*41 (c.233_234delTC) (p.His93Profs*67; c.276_277delTC) (ClinVar=VCV000977782) (PubMed=30737244). Heterozygous for TERT c.1-124C>T (c.228C>T) (C228T); Note=In promoter (PubMed=23833040; PubMed=30737244). Heterozygous for TP53 p.Glu286Val (c.857A>T) (ClinVar=VCV000376592) (PubMed=30737244). Disease Thyroid gland papillary carcinoma (NCIt: C4035) Differentiated thyroid carcinoma (ORDO: Orphanet_146) Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606) Sex of cell Male Age at sampling 74Y Category Cancer cell line STR profile Source(s): ATCC; PubMed=25427145; PubMed=30737244 Markers: Amelogenin X,Y CSF1PO 11,12 D5S818 11 D7S820 9,10 D13S317 12 D16S539 10,12 TH01 8,9.3 TPOX 8,11 vWA 17,18 Run an STR similarity search on this cell line Publications PubMed=23833040; DOI=10.1210/jc.2013-2383 Landa I., Ganly I., Chan T.A., Mitsutake N., Matsuse M., Ibrahimpasic T., Ghossein R.A., Fagin J.A. Frequent somatic TERT promoter mutations in thyroid cancer: higher prevalence in advanced forms of the disease. J. Clin. Endocrinol. Metab. 98:E1562-E1566(2013)
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Cell line name MDA-T32 Comments Omics: Transcriptome analysis. Sequence variations Heterozygous for BRAF p.Val600Glu (c.1799T>A) (ClinVar=VCV000013961) (PubMed=23833040; PubMed=25427145; PubMed=30737244). Heterozygous for CDKN2A p.Leu78Hisfs*41 (c.233_234delTC) (p.His93Profs*67; c.276_277delTC) (ClinVar=VCV000977782) (PubMed=30737244). Heterozygous for TERT c.1-124C>T (c.228C>T) (C228T); Note=In promoter (PubMed=23833040; PubMed=30737244). Heterozygous for TP53 p.Glu286Val (c.857A>T) (ClinVar=VCV000376592) (PubMed=30737244). Disease Thyroid gland papillary carcinoma (NCIt: C4035) Differentiated thyroid carcinoma (ORDO: Orphanet_146) Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606) Sex of cell Male Age at sampling 74Y Category Cancer cell line STR profile Source(s): ATCC; PubMed=25427145; PubMed=30737244 Markers: Amelogenin X,Y CSF1PO 11,12 D5S818 11 D7S820 9,10 D13S317 12 D16S539 10,12 TH01 8,9.3 TPOX 8,11 vWA 17,18 Run an STR similarity search on this cell line Publications PubMed=23833040; DOI=10.1210/jc.2013-2383 Landa I., Ganly I., Chan T.A., Mitsutake N., Matsuse M., Ibrahimpasic T., Ghossein R.A., Fagin J.A. Frequent somatic TERT promoter mutations in thyroid cancer: higher prevalence in advanced forms of the disease. J. Clin. Endocrinol. Metab. 98:E1562-E1566(2013)
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Website网址: http://www.biovector.net
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