Lactococcus lactis CNCM I-4693 strain菌株菌种 BioVector NTCC质粒载体菌种细胞基因保藏中心

Lactococcus lactis CNCM I-4693 strain菌株菌种

the cultivation of this strain on a medium MRS or M20, modified or not, produces a supernatant having a bactericidal effect vis-à-vis Brevibacterium epidermis and casei, im plicated in the unpleasant odors that emerge from the feet as well as with respect to Propionibacterium species involved in the development of acne. Another subject of the invention is a cosmetic or dermatological use for topical use of one or more of these active principles. As described in detail in the examples, the authors identified strains, and in particular a strain of the species Lactococcus lactis, and selected a culture medium for producing an active mixture having a bactericidal effect against of bacteria of the cutaneous human microflora, and more precisely with respect to Brevibacterium bacteria responsible for the body odors and Propionibacterium involved in the development of acne. This strain of Lactococcus lactis was deposited at the National Collection of Microorganism Cultures (CNCM) of the Pasteur Institute, depositary authority under the Budapest Treaty and under the accession number of the deposit CNCM 1-4693. A medium that is particularly suitable for obtaining an active active ingredient that is effective against Brevibacterium and in particular Brevibacterium epidermidis is chosen from the commercially available M20 and MRS media, as well as those mediums whose sugar, namely glucose, has been replaced by another. sugar, or whose concentration has been increased. A preferred glucose replacement sugar is sucrose. Another object of the invention is therefore a deodorant composition or acne control or prevention composition comprising an active ingredient obtained by culturing the strain Lactococcus lactis CNCM 1-4693.

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