iMOSEC cell line鼠永生化卵巢表面上皮细胞株 BioVector NTCC质粒载体菌种细胞基因保藏中心

iMOSEC cell line鼠永生化卵巢表面上皮细胞株

The Immortalized Ovarian Surface Epithelial Cells (iMOSEC) is derived by co-expression of adenovirus E1A and dominant-negative p53 (p53DD). In addition to its non-tumorigenicity, this cell line maintains its primary phenotype and expresses epithelial-specific markers such as E-cadherin, cytokeratin 8 and 18. This cell line is a useful model for studying ovary growth regulation.

Organism
Mus musculus, 11-week-old adult female C57B/6 mouse
Source
Ovarian surface
Culture Properties
Adherent
Morphology
Cuboidal
Immortalization Method
Serial passaging and electroporation transfection with linearized DNA of E1A and p53DD
Markers
E-cadherin, cytokeratin 8 and cytokeratin 18

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