STING基因表达质粒敲除载体TMEM173 BioVector NTCC质粒载体菌种细胞基因保藏中心
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- 货 号:STING基因表达质粒敲除载体TMEM173
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STING基因表达质粒敲除载体TMEM173
RefSeq NM_198282.1, NM_198282.2, NM_198282.3, NM_198282.4, NP_938023.1 RefSeq Size 2223 bp RefSeq ORF 1140 bp Locus ID 340061 Protein Pathways Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway MW 42.2 kDa Gene Summary This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
Supplier来源:BioVector NTCC Inc.
TEL电话:+86-010-53513060
Website网址: http://www.biovector.net
RefSeq NM_198282.1, NM_198282.2, NM_198282.3, NM_198282.4, NP_938023.1 RefSeq Size 2223 bp RefSeq ORF 1140 bp Locus ID 340061 Protein Pathways Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway MW 42.2 kDa Gene Summary This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
Supplier来源:BioVector NTCC Inc.
TEL电话:+86-010-53513060
Website网址: http://www.biovector.net
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