Adult/T315I cell line细胞株细胞系 BioVector NTCC质粒载体菌种细胞基因保藏中心

Adult/T315I cell line细胞株细胞系 BioVector NTCC质粒载体菌种细胞基因保藏中心
Cell line name Adult/T315I
Accession CVCL_5K96

Sequence variations ABL1 p.Thr315Ile (c.1001C>T) (PubMed=21474579).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Adult
Category Cancer cell line
Publications
PubMed=21474579; DOI=10.1158/1078-0432.CCR-11-0234
Nguyen T., Dai Y., Attkisson E., Kramer L., Jordan N., Nguyen N., Kolluri N., Muschen M., Grant S.
HDAC inhibitors potentiate the activity of the BCR/ABL kinase inhibitor KW-2449 in imatinib-sensitive or -resistant BCR/ABL+ leukemia cells in vitro and in vivo.
Clin. Cancer Res. 17:3219-3232(2011)
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